A 6-year-old girl presented with fever, skin rash, anuria, and conjunctivitis that rapidly progressed to toxic shock syndrome. Following hospital discharge, she developed a staphylococcal abscess on the lower extremity. She had recently received the first two doses of the interleukin-17 (IL-17) inhibitor secukinumab for resistant plaque psoriasis. IL-17 is known to be essential in host defense against Staphylococcus aureus. To our knowledge, this is the first reported case of staphylococcal toxic shock syndrome (STSS) associated with an IL-17 inhibitor.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/pde.14228 | DOI Listing |
Publication Analysis
Top Keywords
toxic shock
12
shock syndrome
12
staphylococcal toxic
8
il-17 inhibitor
8
syndrome child
4
child with interleukin-17 inhibitor
4
with interleukin-17 inhibitor treatment
4
treatment psoriasis
4
psoriasis 6-year-old
4
6-year-old girl
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!