Millions of people worldwide use nutritional and dietary supplements, such as vitamins and minerals. These and other performance-enhancing substances are also used by high school, college, and professional athletes, bodybuilders, and amateur sports enthusiasts. The constituents of these supplements and their metabolites may be harmful and not listed on the product label. We present a case report of a 32-year-old bodybuilder using myriad nutritional, performance-enhancing, and weight-loss supplements with life-threatening encephalopathy, hepatic failure, rhabdomyolysis, and copper toxicity mimicking Wilson's disease. Emergency physicians and nurses should be aware of these potential deleterious effects and inquire about supplement use by patients with unexplained multiorgan failure. Family, friends, or acquaintances should be asked to bring the actual products to the hospital for analysis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ajem.2020.05.096 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
GSH/pH-responsive copper-based cascade nanocomplexes inducing immunogenic cell death through cuproptosis/ferroptosis/necroptosis in oral squamous cell carcinoma.
Mater Today Bio
February 2025
Stomatology Department, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, China.
Oral squamous cell carcinoma (OSCC) remains a formidable challenge due to high recurrence rates and limited efficacy of conventional treatments. Immunotherapy holds potential, but its effectiveness is often restricted by low patient responsiveness. This study presents a novel therapeutic strategy using GSH/pH-responsive copper-based cascade nanocomplexes to induce immunogenic cell death (ICD) in OSCC.
View Article and Find Full Text PDFComparative toxicity of copper and zinc contaminated wastewater irrigation on growth, physiology, and mineral absorption of wheat.
Water Environ Res
January 2025
Agrobiology Laboratory, Institute of Agriculture, Lithuanian Research Centre for Agriculture and Forestry (LAMMC), Lithuania.
A comparative pot study was performed to assess the toxic effects of copper (Cu) and/or zinc (Zn) contaminated wastewater (WW) irrigation on the growth, physiology, and element concentration of wheat grown for two months. The treatments included irrigation with uncontaminated wastewater (WW) as control, Cu-contaminated WW (CuWW), Zn-contaminated WW (ZnWW), and Cu + Zn contaminated WW (CuZnWW) in a completely randomized design. Compared to ZnWW, irrigation with CuWW or CuZnWW had severe effects on growth, physiology, and mineral absorption by wheat.
View Article and Find Full Text PDFSensing array based on imidazole-regulated Cu@MOFs nanozymes with enhanced laccase-like activity for the discrimination of phenolic pollutants.
Anal Chim Acta
February 2025
School of the Environment and Safety Engineering, School of the Emergency Management, Jiangsu University, Zhenjiang, 212013, China; Center for Medical Laboratory Science, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, China; Key Laboratory of Clinical Molecular Diagnosis and Research for High Incidence Diseases in Western Guangxi, Guangxi, 533000, China. Electronic address:
Background: Phenolic pollutants with high toxicity and low biodegradability can disrupt environmental balance and severely affect human health, whereas existing methods are difficult to implement the rapid and high-throughput detection of multiple phenolic pollutants.
Results: Herein, we developed a four-dimensional colorimetric sensor array based on imidazole-modulated Cu@MOFs for distinguishing and determining phenolic pollutants. Wherein, four Cu@MOFs (ATP@Cu, ADP@Cu, AMP@Cu, and GMP@Cu) nanozyme with laccase-like activity were firstly prepared, and a novel strategy of imidazole-containing molecules-regulated was proposed to improve the laccase-like activity of Cu@MOFs nanozymes.
Applying hollow octahedron PtNPs/Pd-CuO nanozyme and highly conductive AuPtNPs/Ni-Co NCs to colorimetric -electrochemical dual-mode aptasensor for AFB1 detection.
Anal Chim Acta
February 2025
College of Food Science and Technology, Henan Key Laboratory of Cereal and Oil Food Safety Inspection and Control, Henan University of Technology, Zhengzhou, 450001, China.
Background: Aflatoxin B1 (AFB1) is a secondary metabolite produced by Aspergillus flavus and Aspergillus parasiticus. This toxin is highly carcinogenic and toxic, posing a serious threat to human and animal health. AFB1 primarily enters the human body through contaminated food, particularly peanuts, corn, nuts, and wheat.
View Article and Find Full Text PDFMixed-phase enabled high-rate copper niobate anodes for lithium-ion batteries.
J Mater Chem A Mater
January 2025
MESA+ Institute for Nanotechnology, University of Twente 7500 AE Enschede Netherlands
The advancement of rapid-response grid energy storage systems and the widespread adoption of electric vehicles are significantly hindered by the charging times and energy densities associated with current lithium-ion battery technology. In state-of-the-art lithium-ion batteries, graphite is employed as the standard negative electrode material. However, graphite suffers from polarization and deteriorating side-reactions at the high currents needed for fast charging.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!