The shear force along convergent plate boundary faults (megathrusts) determines the height of mountain ranges that can be mechanically sustained. However, whether the true height of mountain ranges corresponds to this tectonically supported elevation is debated. In particular, climate-dependent erosional processes are often assumed to exert a first-order control on mountain height, although this assumption has remained difficult to validate. Here we constrain the shear force along active megathrusts using their rheological properties and then determine the tectonically supported elevation using a force balance model. We show that the height of mountain ranges around the globe matches this elevation, irrespective of climatic conditions and the rate of erosion. This finding indicates that mountain ranges are close to force equilibrium and that their height is primarily controlled by the megathrust shear force. We conclude that temporal variations in mountain height reflect long-term changes in the force balance but are not indicative of a direct climate control on mountain elevation.
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http://dx.doi.org/10.1038/s41586-020-2340-7 | DOI Listing |
This study aimed to investigate the impact of dietary soybean oil and probiotics on goat meat quality, total conjugated linoleic acids (TCLA) concentration, and nutritional quality indicators of goats. Thirty-six male crossbred goats (Anglo-Nubian♂× Thai native♀), weighing 18.3 ± 2.
View Article and Find Full Text PDFMetabolomics
January 2025
Laboratory of Applied Mass Spectrometry, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
Introduction: Hemodynamic forces play a crucial role in modulating endothelial cell (EC) behavior, significantly influencing blood vessel responses. While traditional in vitro studies often explore ECs under static conditions, ECs are exposed to various hemodynamic forces in vivo. This study investigates how wall shear stress (WSS) influences EC metabolism, focusing on the interplay between WSS and key metabolic pathways.
View Article and Find Full Text PDFJ Thorac Dis
December 2024
College of Chemistry and Life Science, Beijing University of Technology, Beijing, China.
Background: Left ventricular assist device (LVAD) has been widely used as an alternative treatment for heart failure, however, aortic regurgitation is a common complication in patients with LVAD support. And the O-A angle (the angle between LVAD outflow graft and the aorta) is considered as a vital factor associated with the function of aortic valve. To date, the biomechanical effect of the O-A angle on the aortic valve remains largely unknown.
View Article and Find Full Text PDFBiophys Rev
December 2024
James Watt School of Engineering, University of Glasgow, Glasgow, UK.
Mechanosensitivity is the ability of cells to sense and respond to mechanical stimuli. In order to do this, cells are endowed with different components that allow them to react to a broad range of stimuli, such as compression or shear forces, pressure, and vibrations. This sensing process, mechanosensing, is involved in fundamental physiological mechanisms, such as stem cell differentiation and migration, but it is also central to the development of pathogenic states.
View Article and Find Full Text PDFBacteria engage in surface-specific behaviors that are assumed to be driven by biological signaling. However, surface behaviors could be controlled by mechanical reorientation of bacterial appendages. Here, we use microfluidics and flagellar labeling to discover how shear force bends flagella to control surface behavior of the human pathogen .
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