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[Overview of the French Memory Centres healthcare pathway for patients with early Alzheimer disease].
Geriatr Psychol Neuropsychiatr Vieil
September 2024
CMRR CHU Toulouse, IHU Health Age, Toulouse, UMR 1297 CERPOP.
The growing prevalence of the Alzheimer's disease (AD) is an increasing public health concern that led to French recommendations for timely AD diagnosis and patient management as well as a territorial coverage of specialized structures [Memory Centers including Resources and Memory Research Centers (RMRC) and Memory Consultations (MC)]. In view of the potential availability of Disease Modifying Therapies (DMTs), this French observatory aimed to describe the current organization of the Memory Centers, and the care pathway of patients suffering from early AD. Overall, 12 of the 28 RMRC and 44 of the 250 MC solicited by the Federation of Memory Centers participated in this study.
View Article and Find Full Text PDFUtilizing Targeted Next-Generation Sequencing for Rapid, Accurate, and Cost-Effective Pathogen Detection in Lower Respiratory Tract Infections.
Infect Drug Resist
January 2025
Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China.
Objective: To evaluate the diagnostic performance and clinical impact of targeted next-generation sequencing (tNGS) in patients with suspected lower respiratory tract infections.
Methods: Following propensity score matching, we compared the diagnostic performances of tNGS and metagenomic next-generation sequencing (mNGS). Furthermore, the diagnostic performance of tNGS was compared with that of culture, and its clinical impact was assessed.
Evaluation of Male Gonadal Radiation Dose in Abdominal X-ray Examinations: The Impact of Radiographic Projections and Kilovoltage Peak (kVp).
Cureus
December 2024
Department of Diagnostic Imaging and Radiotherapy, Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, Kuantan Campus, Kuantan, MYS.
In abdominal X-ray examinations, radiosensitive organs such as the gonads within or near the imaging region are at risk of radiation exposure. Minimizing the dose to these organs is crucial to reducing unnecessary radiation. This study utilized optically stimulated luminescence dosimeters (OSLDs) to measure the radiation dose to the male gonads at varying kilovoltage peak (kVp) settings while keeping the milliampere-seconds (mAs) constant across different radiographic projections.
View Article and Find Full Text PDFBeyond the Operating Room: A Narrative Review of Enhanced Recovery Strategies in Colorectal Surgery.
Cureus
December 2024
Surgery, Imam Abdulrahman Bin Faisal University, Dammam, SAU.
Enhanced Recovery After Surgery (ERAS) protocols have significantly transformed the management of patients undergoing colorectal surgery. This comprehensive review explores the key components and benefits of ERAS in colorectal procedures, focusing on preoperative, perioperative, and postoperative strategies aimed at improving patient outcomes. These strategies include preoperative patient education, multimodal analgesia, minimally invasive surgical techniques, and early mobilization.
View Article and Find Full Text PDFHyperammonemia and Impaired Consciousness Caused by Non-Urease-Producing Actinotignum schaalii in Obstructive Urinary Tract Infection.
Cureus
December 2024
Emergency and Critical Care Medicine, Iizuka City Hospital, Iizuka, JPN.
Urinary tract infections (UTIs) caused by urease-producing bacteria are known to cause hyperammonemia; however, non-urease-producing bacteria can also cause it. This report describes a case of an 87-year-old woman who developed hyperammonemia and impaired consciousness resulting from a UTI caused by the non-urease-producing bacterium, (). On admission, the patient presented with urinary retention, hyperammonemia (281 μg/dL), and alkaline urine (pH 8.
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