In this issue of , Huang et al have identified activating transcription factor 4 (ATF4) as a novel regulator of fetal γ-globin gene expression in human cells by repressing BCL11A transcription.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290098 | PMC |
http://dx.doi.org/10.1182/blood.2020006300 | DOI Listing |
Mol Breed
February 2025
National Nanfan Research Institute (Sanya), Chinese Academy of Agricultural Sciences, Sanya, 572024 China.
Unlabelled: Chickpea (. L) holds the esteemed position of being the second most cultivated and consumed legume crop globally. Nevertheless, both biotic and abiotic constraints limit chickpea production.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
January 2025
Clinical Research Development Unit of Shahada Hospital in Behshahr, School of Medicine, Mazandaran University of Medical Sciences, Behshahr, Iran.
Background: Stress plays an important role in the consequences of gestational diabetes mellitus [GDM]. It is possible to make a change in the lifestyle by providing counseling in the field of self-care based on stress management in order to avoid the adverse consequences of GDM. Therefore, the present study was designed and implemented with the aim of determining the effect of self-care counseling based on stress management on blood sugar control in women with GDM.
View Article and Find Full Text PDFGlia
January 2025
Kentucky Spinal Cord Injury Research Center, University of Louisville, School of Medicine, Louisville, Kentucky, USA.
Cellular stressors inhibit general protein synthesis while upregulating stress response transcripts and/or proteins. Phosphorylation of the translation factor eIF2α by one of the several stress-activated kinases is a trigger for such signaling, known as the integrated stress response (ISR). The ISR regulates cell survival and function under stress.
View Article and Find Full Text PDFAm J Ind Med
February 2025
Division of Occupational, Environmental, and Climate Medicine, University of California San Francisco, San Francisco, California, USA.
Sci Total Environ
January 2025
Department of Environmental Health Sciences, School of Public Health, University at Albany, State University of New York, Rensselaer, NY, USA. Electronic address:
Climate change has increased the frequency and severity of extreme heat events globally, adversely affecting socio-economic conditions and public health. However, extreme heat has disparate effects on different population groups and the socio-economic determinants of its health effects are not well understood. In this study, we analyzed the spatial patterns of heat-related illness (HRI) visit rates at the zip-code level in Florida and applied statistical methods to examine the relationships between HRIs and environmental and socio-economic variables.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!