Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1001/jamaophthalmol.2019.2670 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
[Not Available].
Tunis Med
October 2024
Ophthalmology Department, Fattouma Bourguiba University Hospital, Monastir. Faculty of Medicine of Monastir, University of Monastir, Tunisia.
Article Synopsis
- The study aimed to analyze microvascular changes around the optic nerve in patients with optic neuropathies using optical coherence tomography angiography (OCTA).
- During the research, 63 eyes from patients with various optic neuropathy causes were compared to 36 healthy eyes, revealing more vascular changes in acute non-arteritic ischemic optic neuropathy than in optic neuritis.
- Results indicated that a lower peripapillary vascular density (PVD) was linked to optic atrophy and hypertension, with some correlations between visual acuity and PVD, highlighting significant changes in microvasculature related to the condition and systemic health factors.
Association of Lipopolysaccharide-Type Endotoxins with Retinal Neurodegeneration: The Alienor Study.
Ophthalmol Sci
August 2024
University of Bordeaux, INSERM, BPH, U1219, F-33000 Bordeaux, France.
Purpose: Lipopolysaccharide (LPS)-type endotoxins are naturally found in the gut microbiota and there is emerging evidence linking gut microbiota and neuroinflammation leading to retinal neurodegeneration. Thinning of the retinal nerve fiber layer (RNFL) is a biomarker of retinal neurodegeneration, and a hallmark of glaucoma, the second leading cause of blindness worldwide. We assessed the association of a blood biomarker of LPS with peripapillary RNFL thickness (RNFLT) and its longitudinal evolution up to 11 years.
View Article and Find Full Text PDFChoroid Involvement Secondary to Optic Disc Pit Maculopathy: OCT Analysis and Evolution After Surgical Treatment.
Am J Ophthalmol
February 2025
From the Ophthalmology Department (M.M.C., F.B., F.G., E.C., S.R.), "Fondazione Policlinico Universitario A. Gemelli, IRCCS", Rome, Italy; Ophthalmology Department (M.M.C., F.B., F.G., E.C., T.C., S.R.), Catholic University "Sacro Cuore", Rome, Italy; Consiglio Nazionale delle Ricerche (S.R.), Istituto di Neuroscienze, Pisa, Italy.
Purpose: To assess choroidal changes associated to optic disc pit maculopathy (ODP-M) and their evolution after surgical treatment.
Design: Multicentric retrospective case series.
Methods: An analysis of 42 patients affected by unilateral ODP-M undergoing surgical treatment between 2013 and 2023 was conducted.
Purpose: To compare children's stereometric optic disc parameters and inner retinal thickness measured by optical coherence tomography (OCT) in two different moments in life in the same children and to establish a correlation between the optic nerve head (ONH) area and the difference of these parameters in the two observations.
Methods: In this observational cohort, children were evaluated on two occasions: at 6.7 ± 1.
Evolution of retinal degeneration and prediction of disease activity in relapsing and progressive multiple sclerosis.
Nat Commun
June 2024
Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Article Synopsis
- Retinal optical coherence tomography (OCT) serves as a biomarker for tracking disease progression in relapsing-remitting multiple sclerosis (RRMS), although the changes in retinal layers for progressive MS remain uncertain.
- Analyzing data from 195 RRMS, 87 secondary progressive MS (SPMS), 125 primary progressive MS (PPMS), and 98 control patients, researchers found that certain retinal layer thicknesses could predict relapses and MRI activity in various MS types.
- However, the variability in measuring retinal thickness limits the effectiveness of longitudinal assessments for individual patients.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!