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Intracranial hypertension and papilledema secondary to an unruptured arteriovenous malformation: Review of the literature.
Neuroradiol J
November 2024
Department of Neurosurgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Arteriovenous malformations (AVMs) are abnormal connections of arteries and veins without intermediate capillary components. As such, AVMs can remain asymptomatic or have a variety of clinical presentations ranging from mild headaches to severe symptoms like seizures, hemorrhage, and subsequent coma. Papilledema and increased intracranial pressure without hydrocephalus or hemorrhage are rare forms of presentations of cerebral AVM.
View Article and Find Full Text PDFIs the presence of peripapillary hyperreflective ovoid mass-like structures (PHOMS) in children related to the optic disc area, scleral canal diameter and refractive status?
Eye (Lond)
October 2024
University Hospital of Wales, Cardiff & Vale University Health Board, Cardiff, UK.
Purpose: Peripapillary hyperreflective ovoid mass-like structures (PHOMS) have been recently described on optical coherence tomography (OCT) scans of the optic nerve. We aim to determine if there is a causal relationship between OCT measurements of the optic disc area (DA), scleral canal diameter (SCD) and refractive error (spherical equivalent, SE) on the presence of PHOMS.
Methods: Retrospective analysis of OCT scans which were graded for the presence or absence of PHOMS in children with suspected papilledema was undertaken.
Are Peripapillary Hyperreflective Ovoid Mass-like Structures with an Elevated Optic Disc Still a Diagnosis Dilemma?
Ophthalmology
September 2024
Department of Neuro-Ophthalmology, Rothschild Foundation Hospital, Paris, France.
Article Synopsis
- The study aimed to identify clinical features that could help diagnose or rule out idiopathic intracranial hypertension (IIH) in patients referred for papilledema, particularly those with specific eye structures called PHOMS.
- Researchers analyzed data from 154 patients, noting that many cases of PHOMS were linked to IIH, though only a small percentage were confirmed; the majority of MRI interpretations were suggestive, but had low sensitivity and specificity.
- The results showed that PHOMS were more frequently found in the nasal region and that their volume was notably larger in patients with IIH, indicating potential clinical markers for this condition.
Highlights of ophthalmological manifestations in newly diagnosed acute leukemia: a correlation with hematological parameters.
Ann Hematol
September 2024
Hematology Unit, Internal Medicine Department, Oncology Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Acute leukemia is a hematological malignancy affecting different organ systems including the eye and orbit through direct infiltration of tissues or secondary to hematological abnormalities. Ophthalmological manifestations in acute leukemia are variable ranging from asymptomatic presentation to serious manifestations that can alter the disease course and treatment. The purpose of this study is to detect the incidence of different ophthalmological manifestations in newly diagnosed acute leukemia patients and to assess the relationship between ocular findings and hematological characteristics and the sequel of these neoplasms.
View Article and Find Full Text PDFVisual and Pharmacotherapy Outcomes After Transverse Sinus Stenting for Idiopathic Intracranial Hypertension.
J Neuroophthalmol
April 2024
Faculty of Medicine (AH, JM, EM), Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada; Michael G. DeGroote School of Medicine (JSX), McMaster University, Hamilton, Canada; Faculty of Medicine (EH, PM, PN), Division of Neuroradiology, Department of Medical Imaging, University of Toronto, Toronto, Canada; Faculty of Medicine (JM, EM), Division of Neurology, Department of Medicine, University of Toronto, Toronto, Canada; and Kensington Vision and Research Center (JM), Toronto, Canada.
Background: Transverse sinus stenting (TSS) is an increasingly common treatment for patients with idiopathic intracranial hypertension (IIH). However, detailed neuro-ophthalmic evidence on visual and pharmacotherapy outcomes after TSS is scarce and heterogeneous. This study aimed to describe the visual outcomes of patients undergoing TSS for IIH and to ascertain the proportion of patients who could be weaned off intracranial pressure (ICP)-lowering medication postoperatively.
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