Purpose: To compare the differences of influence of mothers' different socio-demographic background, their oral health status and feeding behavior on their one-month-old infants' risk of dental caries between Shanghai and Kunming, and to explore the factors affecting infants' risk of dental caries in different regions.

Methods: One-month-old infants and their mothers from Huangpu district of Shanghai and Xishan district of Kunming were recruited in the study. Oral plaque samples of mothers and their infants were collected to assess their risk of dental caries. Statistical analysis was performed using SPSS 22.0 software package, and multivariate logistic regression analysis was used to screen the factors affecting the risk of infantile rickets in Shanghai and Kunming.

Resulits: A total of 165 mother-child pairs in Shanghai and 161 mother-child pairs in Kunming participated in the survey, and the proportion of infants who were at high risk of caries was 10.3% and 6.2%, respectively. The result of multivariate logistic analysis indicated that the infants whose mother smoked before pregnancy (OR=6.9, P=0.030) and attained lower education level (OR=6.1, P=0.035) had higher risk of caries in Shanghai; while in Kunming, the infants whose mother had higher DMFS values were at higher risk of caries (OR=1.1, P=0.031).

Conclusions: Factors affecting one-month-old infants' risk of caries in Shanghai and Kunming were pre-pregnancy maternal cigarette smoking, mother's lower education level and mother's dental caries status, respectively.

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