The title compound, 2-(3-cyano-4-iso-but-oxyphen-yl)-4-methyl-1,3-thia-zole-5-car-b-oxy-lic acid ethanol monosolvate, CHNOS·CHO, (I), displays inter-molecular O-H⋯O and O-H⋯N bonds in which the carboxyl group of the febuxostat mol-ecule and the hydroxyl group of the ethanol mol-ecule serve as hydrogen-bond donor sites. These inter-actions result in a helical hydrogen-bonded chain structure. The title structure is isostructural with a previously reported methanol analogue.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273979 | PMC |
| http://dx.doi.org/10.1107/S2056989020006076 | DOI Listing |
Publication Analysis
Top Keywords
ethanol monosolvate
8
febuxostat ethanol
4
monosolvate title
4
title compound
4
compound 2-3-cyano-4-iso-but-oxyphen-yl-4-methyl-13-thia-zole-5-car-b-oxy-lic
4
2-3-cyano-4-iso-but-oxyphen-yl-4-methyl-13-thia-zole-5-car-b-oxy-lic acid
4
acid ethanol
4
monosolvate chnos·cho
4
chnos·cho displays
4
displays inter-molecular
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!