AI Article Synopsis
- Castleman's disease is a rare condition characterized by enlarged lymph nodes, and this study explores the use of video-assisted thoracoscopic surgery (VATs) as a diagnostic and treatment option for intrathoracic unicentric Castleman's disease (UCD).
- Between January 2010 and June 2018, 10 patients had VATs for UCD, with the majority having successful complete surgical excisions, and no postoperative complications were reported.
- The results suggest that VATs is a safe and effective minimally invasive technique for both diagnosing and treating intrathoracic UCD, as most patients showed no signs of tumor recurrence after a median follow-up of 5 years.
Article Abstract
Background: Castleman's disease (CD) is a rare non-clonal lymphadenopathy. Application of video-assisted thoracoscopic surgery (VATs) in intrathoracic unicentric Castleman's disease (UCD) is rarely reported. This study is aimed to clarify the role of VATs for diagnosis and treatment in intrathoracic UCD.
Methods: The authors reviewed and identified patients who had received a histologic diagnosis of CD through VATs at our hospital from January2010 to June 2018. Clinical and radiologic variables, histopathology, type of approach, complications, and long-term effect were analyzed to evaluate the safety and efficacy of VATs.
Results: A total of 10 patients were included in this study, with 8 hyaline vascular type and 2 plasma cell type. The mean maximum diameter of the lesions was 4.66 cm. Nine cases underwent complete surgical excision by VATs, and 1 case was converted to thoracotomy. All patients had no postoperative complications. With a median follow-up of 5 years (range: 1-9 years), no tumor recurrence was found in 9 patients receiving complete tumor resection, and 1 patient with incomplete tumor resection remained symptom free without clinical or radiographic progression.
Conclusions: VATs is an alternative, minimally invasive technique for the diagnosis and treatment in patients with intrathoracic UCD.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285469 | PMC |
| http://dx.doi.org/10.1186/s12893-020-00789-6 | DOI Listing |
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