Drug adulterants containing contaminants have been known to cause lung disease by inhalation or intravenous intake. Talcosis due to intravenous talc injection has been widely described in the literature, whereas the hypothesis of granulomatosis due to asbestos related to adulterated cocaine injection has not yet been explored. Herein, a case of pulmonary granulomatosis due to asbestos fibres related to cocaine injection in a young woman is described. Inorganic material in the lung was first individuated by light microscopy and last was identified using the SEM-EDX method. This case is unique since the occupational and passive inhalation of asbestos was excluded with absolute certainty.
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http://dx.doi.org/10.1007/s00428-020-02863-z | DOI Listing |
Arthritis Rheumatol
September 2021
University of Florence, Florence, Italy.
Objective: Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Environmental agents and occupational exposures may confer susceptibility to EGPA, but data are scarce. This study was undertaken to investigate the association between occupational exposures (e.
View Article and Find Full Text PDFSarcoidosis Vasc Diffuse Lung Dis
November 2020
Service de Pneumologie et d'explorations fonctionnelles respiratoires, CHU Bretonneau, Tours, France.
Background: Forms of interstitial pneumonia secondary to exposure to an air-contaminant are varied and so far, insufficiently described.
Objectives/methods: We report here a case of a 57-year-old patient managed in our department for the exploration of MRC grade 2 dyspnoea and interstitial pneumonia. He mentioned multiple occupational and domestic exposures such as hens' excrements, asbestos and metal particles; he also had a previous history of smoking.
Virchows Arch
February 2021
Department of Health Care Surveillance and Bioetics, Section of Legal Medicine, Università Cattolica del Sacro Cuore, Rome, Italy.
Drug adulterants containing contaminants have been known to cause lung disease by inhalation or intravenous intake. Talcosis due to intravenous talc injection has been widely described in the literature, whereas the hypothesis of granulomatosis due to asbestos related to adulterated cocaine injection has not yet been explored. Herein, a case of pulmonary granulomatosis due to asbestos fibres related to cocaine injection in a young woman is described.
View Article and Find Full Text PDFSci Total Environ
April 2001
Department of Internal Medicine, University of Torino, S. Giotanni Molinette Hospital, Italy.
Background: A possible relationship between Silica (Si) exposure and antineutrophil cytoplasm antibodies (ANCA)-associated vasculitis has been reported. Furthermore, tuberculosis (TBC) has been frequently described in patients with silicosis, and TBC infection shares with ANCA-associated vasculitis the formation of granulomas. Therefore, an intriguing network including Silica, Vasculitis, TBC and ANCA might be hypothesized.
View Article and Find Full Text PDFLung
May 1991
Department of Pathology, Mount Sinai School of Medicine, City University of New York, New York.
A patient with pulmonary asbestosis developed hemoptysis and a lesion on chest radiograph secondary to bronchocentric granulomatosis (BG) associated with Aspergillus fumigatus. Although pulmonary Aspergillus infection is a known complication of asbestos exposure. BG has not been previously reported in this disorder.
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