This study aimed to collect and analyze photon beam data for the Varian C-series linear accelerators (Varian Medical Systems, Palo Alto, CA, USA). We evaluated the potential of the average data to be used as reference beam data for the radiotherapy treatment planning system commissioning verification. We collected 20 data sets for 4 and 6 MV photon beams, and 40 data sets for a 10 MV photon beam generated by the Varian C-series machines, which contained the percent depth dose (PDD), off-center ratio (OCR), and output factor (OPF) from 20 institutions. The average for each of the data types was calculated across the 20 machines. Dose differences from the average for PDD at the dose fall-off region were less than 1.0%. Relative differences from the average for the OPF data were almost within 1.0% for all energies and field sizes. For OCR data in the flat regions, the standard deviation of the dose differences from the average was within 1.0%, excluding that of the 30 × 30 mm field size being approximately 1.5%. For all energies and field sizes, the distance to agreement from the average in the OCR penumbra regions was less than 1.0 mm. The average data except for the small field size found in this study can be used as reference beam data for verifying users' commissioning results.
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http://dx.doi.org/10.1007/s13246-020-00885-0 | DOI Listing |
J Cancer Res Clin Oncol
January 2025
Sarcoma Unit, Department of Surgery, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Purpose: The management of soft tissue sarcoma (STS) at reference centers with specialized multidisciplinary tumor boards (MTB) improves patient survival. The German Cancer Society (DKG) certifies sarcoma centers in German-speaking countries, promoting high standards of care. This study investigated the variability in treatment recommendations for localized STS across different German-speaking tertiary sarcoma centers.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Beijing Yakebot Technology Co., Ltd, F-616-West Building, Yonghe Plaza, No. 28 Andingmen Dongdajie, DongCheng District, Beijing, 100007, China.
Background: The surgical complexity associated with the palatal roots of maxillary molars was considerably elevated. Previous studies on the relationships between maxillary molar roots and the maxillary sinus or cortical plates have focused on individual root observation without considering the positional relationship between buccal and palatal roots or analysing the surgical pathway of maxillary molar palatal roots. This study aimed to investigate the relationship between maxillary molar palatal roots and adjacent anatomical structures to provide a reference for performing palatal roots endodontic microsurgery.
View Article and Find Full Text PDFBrachytherapy
January 2025
Department of Genitourinary Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Background: To determine outcomes of MRI-assisted radiosurgery (MARS) for salvage brachytherapy using the radioisotope Pd after various upfront treatments including surgery, external beam radiotherapy, and brachytherapy.
Methods: We retrospectively reviewed data for patients who underwent salvage MARS for intraprostatic lesions or prostate bed recurrences from 2016 to 2022. Biochemical recurrence, prostate cancer-specific, and overall survival, and the cumulative incidences of toxicities, were determined by Kaplan-Meier estimates.
Phys Med
January 2025
Department of Physics "A. Pontremoli", University of Milan & INFN sez. Milano, Milano, Italy. Electronic address:
Purpose: This work aims at investigating, via in-silico evaluations, the noise properties of an innovative scanning geometry in cone-beam CT (CBCT): eCT. This scanning geometry substitutes each of the projections in CBCT with a series of collimated projections acquired over an oscillating scanning trajectory. The analysis focused on the impact of the number of the projections per period (PP) on the noise characteristics.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
In cases of large mandibular continuity defects resulting from malignancy resection, the current standard of care involves using patient-specific/custom titanium reconstruction plates along with autogenous grafts (fibula, scapula, or iliac crest segments). However, when grafts are not feasible or desired, only the reconstruction plate is used to bridge the gap. Unfortunately, metal osteosynthesis and reconstruction plates, including titanium, exhibit adverse effects such as stress-shielding and limitations in accurate postoperative irradiation (especially with proton-beam therapy).
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