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Delayed cord clamping (DCC) has been widely adopted in both term and preterm infants to improve neonatal outcomes by increasing blood volume and supporting oxygenation. However, the optimal cord management for intrauterine growth-restricted (IUGR) infants is unclear. To systematically review and meta-analyze the effects of DCC compared to early cord clamping (ECC) in IUGR infants.

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Background: Aspirin has proved its efficacy in reducing the rate of preeclampsia in singleton pregnancy, however, there is discrepancy about the efficient dosage that should be used. While some societies recommend daily 75-81mg, others recommend higher dosage (160mg). This discrepancy is due to the lack of randomized controlled studies that compare these two dosages.

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Complications of twin pregnancy such as twin anemia-polycythemia sequence (TAPS), which involve placental anastomotic vessels, occur mostly in monochorionic diamniotic twins and they have rarely been reported in dichorionic diamniotic (DD) twins. Here, we report a case of DD twins diagnosed with TAPS with fetal hydrops caused by fetal anemia at 28 weeks, which resolved spontaneously during pregnancy. A 37-year-old pregnant woman was referred to our hospital because of a twin pregnancy at 13 weeks.

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Article Synopsis
  • * Among 100 TAPS pregnancies, 32% experienced respiratory distress syndrome (RDS), 13% had bronchopulmonary dysplasia (BPD), and 7% had persistent pulmonary hypertension of the newborn (PPHN), with donors showing a higher incidence of PPHN.
  • * The findings indicated that lower gestational age and severe fetal anaemia are significant risk factors for PPHN in TAPS twins, highlighting the need for specialized medical care during birth to manage potential complications.
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