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Vulvar Developmental Stages During Puberty: A Systematic Review.
J Pediatr Adolesc Gynecol
January 2025
Department of Women, Children, and Adolescents, Geneva University Hospitals, Geneva, Switzerland.
Study Objective: Puberty is associated with important changes in secondary sexual characteristics, but the changes occurring in female external genitalia are not thoroughly described. The aim of this systematic review is to summarize and assess the current scientific knowledge regarding vulvar changes and development during puberty.
Methods: PubMed, Embase, Web of Science, and Cochrane were searched, using keywords related to "puberty", "vulva", and "morphology".
Assessing the Diagnostic Performance of Automated Pituitary Gland Volume Measurement for Idiopathic Central Precocious Puberty.
J Clin Med
December 2024
Departments of Radiology, Eulji University Hospital, Eulji University College of Medicine, 95 Dunsanseo-ro, Seo-gu, Daejeon 35233, Republic of Korea.
It is known that the pituitary gland volume (PV) in idiopathic central precocious puberty (IPP) is significantly higher than in healthy children. However, most PV measurements rely on manual quantitative methods, which are time-consuming and labor-intensive. This study aimed to automatically measure the PV of patients with IPP using artificial intelligence to accurately quantify the correlation between IPP and PV, and to improve the efficiency of diagnosing IPP.
View Article and Find Full Text PDFChildhood obesity and central precocious puberty.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
July 2024
Second Ward of Endocrinology Department, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000.
Central precocious puberty (CPP) is an endocrine disorder in children caused by the early activation of the hypothalamic-pituitary-gonadal axis (HPGA), leading to elevated gonadotropin-releasing hormone (GnRH), which triggers the development of gonads and the secretion of sex hormones. This eventually results in the development of internal and external genitalia and secondary sexual characteristics. CPP significantly affects the physical and mental health of children and may increase the risk of various adult diseases.
View Article and Find Full Text PDFVoice self-perception and acoustic parameters in transgirls adolescent related to pubertal stage blockage.
Early Hum Dev
January 2025
Department of Otorhinolaryngology, Puerta del Mar University Hospital, 11009 Cádiz, Spain.
Background: Trans girls may initiate early puberty blockers once puberty has started in order to prevent the development of masculine secondary sexual characteristics. Depending on how early the puberty blockers are administered, voice may have reached a certain degree of development and have acquired typically male acoustic and phonetic parameters, which can cause discomfort and affect the adolescent's quality of life.
Purpose: The aim of the present study was to (1) determine if there are differences in discomfort with the self-perceiver voice according to the moment of puberty block (PB), and (2) find a relation between vocal discomfort and variables such a voice phonetic/acoustic characteristics and self-perception of voice.
Multifaceted delineation of atrophic thyroiditis among pediatric population: An extensive literature survey.
Clin Pediatr Endocrinol
January 2025
Department of Pediatrics, Showa University School of Medicine, Tokyo, Japan.
Autoimmune hypothyroidism is categorized into Hashimoto thyroiditis (HT) and atrophic thyroiditis (AT). Although a consensus exists among Japanese endocrinologists that pediatric AT is associated with severe hypothyroidism, the question remains whether AT and HT are separate conditions. To investigate the clinical characteristics of pediatric AT, we conducted a comprehensive literature review using PubMed and ICHUSHI, a local database.
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