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| http://dx.doi.org/10.1016/j.jcrc.2020.05.015 | DOI Listing |
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Hygrometry behavior during high-flow nasal oxygen therapy and non-invasive mechanical ventilation: A narrative review of bench to clinical studies.
J Intensive Med
October 2024
Intensive Care Unit, Hospital Morales Meseguer, Murcia, Spain.
Recently, there has been growing interest in knowing the best hygrometry level during high-flow nasal oxygen and non-invasive ventilation (NIV) and its potential influence on the outcome. Various studies have shown that breathing cold and dry air results in excessive water loss by nasal mucosa, reduced mucociliary clearance, increased airway resistance, reduced epithelial cell function, increased inflammation, sloughing of tracheal epithelium, and submucosal inflammation. With the Coronavirus Disease 2019 pandemic, using high-flow nasal oxygen with a heated humidifier has become an emerging form of non-invasive support among clinicians.
View Article and Find Full Text PDFPhysiological basis of non-invasive ventilation in the newborn.
Semin Perinatol
December 2024
Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom; Neonatal Intensive Care Unit, University of Patras, Patras, Greece. Electronic address:
Non-invasive ventilation (NIV) is a form of respiratory support provided primarily to preterm born infants in an effort to avoid any endotracheal intubation or as a weaning step following invasive ventilation. In the context of the respiratory distress syndrome of the newborn, NIV could target and partially reverse specific pathophysiological phenomena, by improving alveolar recruitment and establishing adequate functional residual capacity. It can also assist in minimizing lung injury by avoiding excessive pressure delivery, which can be harmful for the developing lung.
View Article and Find Full Text PDFClinical study on the predictive utility of high flow CPAP in weaning from prolonged mechanical ventilation in critical paediatric surgery patients.
Rev Esp Anestesiol Reanim (Engl Ed)
December 2024
Servicio de Anestesiología y Reanimación, Hospital Universitario La Paz, Madrid, Spain.
Introduction And Objectives: Weaning paediatric patients from mechanical ventilation (MV) often results in extubation failure (EF) (14%-22%) and 2% of patients will require tracheostomy (2%).
Methods: We performed an observational study in 115 critically ill patients in whom a novel high-flow CPAP (CPAP-ANRI) system was connected to the tracheal tube during ventilation (CPAP + TI). After extubation, the same system was connected to various interfaces.
Efficacy of high-flow nasal oxygenation during induction of general anaesthesia in parturients living with obesity: a two-centre, prospective, randomised clinical trial.
Anaesthesia
November 2024
Department of Anesthesiology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Article Synopsis
- High-flow nasal oxygenation improves oxygenation during anaesthesia induction for pregnant women with obesity, but its effects compared to standard facemask ventilation were studied due to a lack of existing data.
- A clinical trial involving 54 participants revealed that those using high-flow nasal oxygen had significantly higher oxygen levels after pre-oxygenation compared to the facemask group.
- While high-flow nasal oxygen showed improved oxygenation results, the differences weren’t deemed clinically significant, suggesting it could be a viable option for these patients.
Impact of High-Flow Nasal Cannula Oxygen Therapy on the Pressure of the Airway System in Humans.
Respir Care
October 2024
Mrs Moracci and Plotnikow are affiliated with the Physical and Respiratory Therapy Department, Intensive Care Unit, Hospital Británico de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.
Background: The understanding of how pharyngeal pressure is transmitted to the trachea with high-flow nasal cannula (HFNC) implementation and the behavior of tracheal pressure in the presence of mouth leaks remains limited. This study aimed to assess the impact of HFNC administration on tracheal pressure by comparing measurements taken with open and closed mouth with varying flows.
Methods: A crossover study was conducted between March 2019 and June 2023.
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