During the 2018 eruption of Kīlauea Volcano, Hawai'i, scientists relied heavily on a conceptual model of explosive eruptions triggered when lava-lake levels drop below the water table. Numerical modeling of multiphase groundwater flow and heat transport revealed that, contrary to expectations, liquid water inflow to the drained magma conduit would likely be delayed by months to years, owing to the inability of liquid water to transit a zone of very hot rock. The summit of Kīlauea subsequently experienced an ∼2-month period of consistent repeated collapses, and the crater now extends below the equilibrium position of the water table. Liquid water first emerged into the deepened crater in late July 2019. The timing of first appearance of liquid water (about 14 months postcollapse) and the rate of crater lake filling (currently ∼27 kg/s) were well-predicted by the numerical modeling done in late spring 2018, which forecast liquid inflow after 3 to 24 months at rates of 10 to 100 kg/s. A second-generation groundwater model, reflecting the current crater geometry, forecasts lake filling over the next several years. The successful 2018 to present forecasts with both models are based on unadjusted in situ permeability estimates (1 to 6 × 10 m ) and water-table elevations (600 to 800 m) from a nearby research drillhole and geophysical surveys. Important unknowns that affect the reliability of longer-term forecasts include the equilibrium water-table geometry, the rate of evaporation from the hot and growing crater lake (currently ∼29,000 m at 70-80 °C), and heterogenous permeability changes caused by the 2018 collapse.
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Nat Commun
January 2025
Department of Physics, University of Science and Technology of China, Hefei, Anhui, 230026, China.
Materials with full and fractional skyrmions are important for fundamental studies and can be applied as information carriers for applications in spintronics or skyrmionics. However, creation, direct optical observation and manipulation of different skyrmion textures remain challenging. Besides, how the transformation of skyrmion textures directs the dynamics of colloids is not well understood.
View Article and Find Full Text PDFAnal Chim Acta
March 2025
Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, the Netherlands; Centre for Analytical Sciences Amsterdam, Science Park 904, 1098 XH, Amsterdam, the Netherlands. Electronic address:
Background: Persistent and mobile organic compounds (PMOC) are of great concern for water quality and human health. The recent improvement and availability of high-resolution mass spectrometry in combination with liquid chromatography have widely expanded the potential of analytical workflows for their detection and quantitation in water. Given their high polarity, the detection of some PMOC requires alternative techniques to reversed-phase chromatography, such as hydrophilic interaction liquid chromatography (HILIC) and supercritical fluid chromatography (SFC).
View Article and Find Full Text PDFJ Lipid Res
January 2025
Physiology and Pathophysiology of Cells and Membranes, Medical School OWL, Bielefeld University, Bielefeld, Germany. Electronic address:
The environmental pollutant cadmium (Cd) poses a threat to human health through consumption of contaminated foodstuffs culminating in chronic nephrotoxicity. Mitochondrial dysfunction and excessive reactive oxygen species (ROS) are key to Cd cellular toxicity. Cd-lipid interactions have been less considered.
View Article and Find Full Text PDFJ Pharm Sci
January 2025
Department of Pharmaceutics, College of Pharmacy, King Saud University, POBOX-2457, Riyadh 11451, Kingdom of Saudi Arabia; Kayyali Chair for Pharmaceutical Industries, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia. Electronic address:
Background And Purpose: Liquid self-nanoemulsifying drug delivery systems (SNEDDS) face challenges related to stability, handling, and storage. In particular, lipophilic and unstable drugs, such as ramipril (RMP) and thymoquinone (THQ), face challenges in oral administration due to poor aqueous solubility and chemical instability. This study aimed to develop and optimize multi-layer self-nanoemulsifying pellets (ML-SNEP) to enhance the stability and dissolution of ramipril (RMP) and thymoquinone (THQ).
View Article and Find Full Text PDFEnviron Res
January 2025
Key Laboratory of Regional Environment and Eco-restoration, Ministry of Education, Shenyang University, Shenyang, 110044, Liaoning, China. Electronic address:
Nano-microplastics and 17β-E2 have been frequently detected as emerging high-concern pollutants in aquatic systems, and their interaction at the solid/liquid interface has become a research focus in environmental studies. The interfacial sorption kinetics and equilibrium characteristics of 17β-estradiol (17β-E2) on nano-polystyrene (Nano-PS) with different particle sizes and organic functional group modifications were systematically investigated in aqueous environments in this study. The interfacial interaction mechanism between Nano-PS particles and 17β-E2 was elucidated by utilizing SEM, FTIR, XPS and BET techniques.
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