Carrying a heavy school backpack has extensively been reported as a prime cause of children's body strain. It is suggested that the load should not exceed 10 percent of the child's body weight; however, ensuring this requires continuous monitoring. The study explores how ergonomically designed school backpack based on the user anthropometric data ( = 280) and ergonomic parameters help reduce force concentration on shoulders and back. It provides a validation process of the developed prototype by experimental verification. The developed design was assessed in a comparison experiment with a commercially available local school backpack. An experimental study was used which recruited thirty healthy college students (aged 19 to 23 years). Two independent variables evaluated were school backpack type (developed backpack versus commercial one) and load levels as a percentage of body weight. Three load levels were employed 10%, 15%, and 20%. These variables were measured on the responses: bag comfort scale and the percent of maximum voluntary contraction (%MVC) of six muscles (right and left of erector spine, right and left of external abdominal oblique muscle, and right and left of trapezius). The developed backpack provided astonishing performance at levels of 15% and 20% of body weight in terms of subjective measure and electromyography (EMG) responses. It also showed that increasing the carried weight more than 10% result in reducing activity on the erector spinal muscles, while it increases on abdominal oblique muscles. The developed backpack design confirmed the efficiency of its bases by distributing the carried weight among the trunk through side pockets, attached to the body through two upper and lower straps. It helped the body to distribute the carried weight and avoid concentrating pressure on specific areas.
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http://dx.doi.org/10.1155/2020/1437126 | DOI Listing |
Bioeng Transl Med
January 2025
Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University Boston Massachusetts USA.
Immune checkpoint inhibitors (ICIs) represent new therapeutic candidates against glioblastoma multiforme (GBM); however, their efficacy is clinically limited due to both local and systemic immunosuppressive environments. Hence, therapeutic approaches that stimulate local and systemic immune environments can improve the efficacy of ICIs. Here, we report an adoptive cell therapy employing neutrophils (NE) that are activated via surface attachment of drug-free disk-shaped backpacks, termed Cyto-Adhesive Micro-Patches (CAMPs) for treating GBM.
View Article and Find Full Text PDFEnviron Int
December 2024
Swiss Tropical and Public Health Institute, 4123 Allschwil, Switzerland; University of Basel, 4001 Basel, Switzerland. Electronic address:
Exposure to extremely low frequency magnetic fields (ELF-MF) is ubiquitous in our daily environment. This study aims to provide a comprehensive overview of the ambient ELF-MF exposure in Switzerland and presents a novel environmental exposure matrix for exposure assessment and risk communication. Magnetic flux density levels (µT) were measured using a portable exposimeter carried in a backpack for the main ELF sources: railway power (16.
View Article and Find Full Text PDFPrev Sci
December 2024
The Pennsylvania State University, University Park, USA.
The Research-based Developmentally Informed (REDI) program enriched Head Start classrooms with teacher-delivered curriculum components designed to enhance child social-emotional learning and language-literacy skills. Parents received information about the program via backpack express, including weekly handouts about program topics and three DVDs illustrating REDI interactive strategies and suggesting home learning activities. In addition to effects on child skill acquisition and school performance (reported previously), positive effects emerged on a family-based outcome: parents of children in REDI-enriched classrooms reported higher quality preschool parent-child conversations than parents in the randomized control group (usual practice) classrooms.
View Article and Find Full Text PDFNanoscale
January 2025
Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, Sichuan University, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Bacterial outer membrane vesicles (OMVs), produced by Gram-negative bacteria, retain the immunostimulatory capacity of parental bacteria. OMVs have been recognized as potent natural immune adjuvants and drug delivery vehicles. Photothermal therapy that triggers immunogenic cell death further stimulates the immune system by releasing damage-associated molecular patterns.
View Article and Find Full Text PDFTo (1) estimate the economic cost of disabling musculoskeletal pain in children and adolescents from a health care and societal perspective, (2) identify the characteristics of children and adolescents with higher costs, and (3) estimate the economic cost of children's pain to Brazil. Prospective cohort study. We recruited children and adolescents with disabling musculoskeletal pain from public and private schools.
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