The developing countries are still starving for the betterment of health sector. The disease commonly found among the women is breast cancer, and past researches have proven results that if the cancer is detected at a very early stage, the chances to overcome the disease are higher than the disease treated or detected at a later stage. This article proposed cloud-based intelligent with 2 variations/models like and . The proposed system has employed two main soft computing algorithms. The proposed BCP-T1F-SVM expert system specifically defines the stage and the type of cancer a person is suffering from. Expert system will elaborate the grievous stages of the cancer, to which extent a patient has suffered. The proposed BCP-SVM gives the higher precision of the proposed breast cancer detection model. In the limelight of breast cancer, the proposed BCP-T1F-SVM expert system gives out the higher precision rate. The proposed BCP-T1F expert system is being employed in the diagnosis of breast cancer at an initial stage. Taking different stages of cancer into account, breast cancer is being dealt by BCP-T1F expert system. The calculations and the evaluation done in this research have revealed that is better than . The concludes out the 96.56 percentage accuracy, whereas the gives accuracy of 97.06 percentage. The above unleashed research is wrapped up with the conclusion that is better than the . The opinions have been recommended by the medical expertise of Sheikh Zayed Hospital Lahore, Pakistan, and Cavan General Hospital, Lisdaran, Cavan, Ireland.
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http://dx.doi.org/10.1155/2020/8017496 | DOI Listing |
Discov Oncol
January 2025
Department of Breast Surgery, The First Affiliated Hospital of Harbin Medical University, No. 23, Youzheng Street, Nangang District, Harbin, 150001, China.
Cancer vaccines are promising as an effective means of stimulating the immune system to clear tumors as well as to establish immune surveillance. In this paper, we discuss the main platforms and current status of cancer vaccines and propose a new cancer vaccine platform, the cytosolic vesicle vaccine. This vaccine has a unique structure that can integrate antigen and adjuvant carriers to improve the delivery efficiency and immune activation ability, which brings new ideas for cancer vaccine design.
View Article and Find Full Text PDFUpdates Surg
January 2025
Department of Radiation Oncology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People's Republic of China.
Whether primary lesion surgery improves survival in patients with de novo metastatic breast cancer (dnMBC) is inconclusive. We aimed to establish a prognostic prediction model for patients with de novo metastatic breast invasive ductal carcinoma (dnMBIDC) based on machine learning algorithms and to investigate the value of primary site surgery. The data used in our study were obtained from the Surveillance, Epidemiology, and End Results database (SEER, 2010-2021) and the First Affiliated Hospital of Nanchang University (1st-NCUH, June 2013-June 2023).
View Article and Find Full Text PDFMol Biol Rep
January 2025
Kusuma School of Biological Sciences, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, 110016, India.
Background: Exosomes are extracellular vesicles released by cells that mediate intercellular communication and actively participate in cancer progression, metastasis, and regulation of immune response within the tumour microenvironment. Inhibiting exosome release from cancer cells could be employed as a therapeutic against cancer.
Methods And Results: In the present study, we have studied the effects of Acorus calamus in inhibiting exosome secretion via targetting Rab27a and neutral sphingomyelinase 2 (nSMase2) in HER2-positive (MDA-MB-453), hormone receptor-positive (MCF-7) and triple-negative breast cancer (MDA-MB-231) cells.
Discov Nano
January 2025
Department of Mathematics and Physics "Ennio De Giorgi", University of Salento, Via Arnesano, 73100, Lecce, LE, Italy.
Breast cancer is the most common cancer among women, with over 1 million new cases and around 400,000 deaths annually worldwide. This makes it a significant and costly global health challenge. Standard treatments like chemotherapy and radiotherapy, often used after mastectomy, show varying effectiveness based on the cancer subtype.
View Article and Find Full Text PDFInt J Comput Assist Radiol Surg
January 2025
Pattern Recognition Lab, Friedrich-Alexander-University Erlangen-Nuremberg, Martensstr. 3, 91058, Erlangen, Bayern, Germany.
Purpose: Breast cancer remains one of the most prevalent cancers globally, necessitating effective early screening and diagnosis. This study investigates the effectiveness and generalizability of our recently proposed data augmentation technique, attention-guided erasing (AGE), across various transfer learning classification tasks for breast abnormality classification in mammography.
Methods: AGE utilizes attention head visualizations from DINO self-supervised pretraining to weakly localize regions of interest (ROI) in images.
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