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Essential Oils as Bioinsecticides Against (Linnaeus, 1767): Evaluating Its Efficacy Under a Practical Framework.
Insects
January 2025
Henkel Ibérica S.A, Research and Development (R&D) Insect Control Department, 08005 Barcelona, Spain.
Concerns about the negative effects of traditional insecticides and increasing insecticide resistance have prompted the exploration of botanical alternatives like essential oils (EOs). The registration of biocides is a mandatory procedure, and some regions have established a special status for compounds that meet specific low-risk criteria, which includes certain EOs. This study aimed to evaluate and compare the efficacy of sixteen EOs, both registered as low-risk biocides and/or standard biocides, against the German cockroach, .
View Article and Find Full Text PDFThe Combination Effect of Strain (AUMC 10620) and Avermectin (B1a and B1b) on Control Citrus Nematode (Cobb) Under Laboratory and Field Conditions.
Biology (Basel)
January 2025
Plant Protection Department, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.
This study investigates the nematicidal efficacy of strain (AUMC 10620) combined with avermectin (B1a and B1b) against the citrus nematode , both in vitro and in vivo. Laboratory experiments tested four concentrations of (2.5, 5, 10, and 15 × 10 spores/mL) mixed with 250 ppm avermectin, assessing their effects on nematode juveniles (J2) and eggs.
View Article and Find Full Text PDFThe effects of ultra-selective beta1-antagonism on the metabolic and cytokine profile in septic shock patients receiving noradrenaline: a sub-investigation from the STRESS-L Randomised Study.
Intensive Care Med Exp
January 2025
Department of Life Sciences, Aberystwyth University, Ceredigion, UK.
Purpose: The landiolol and organ failure in patients with septic shock (STRESS-L study) included a pre-planned sub-study to assess the effect of landiolol treatment on inflammatory and metabolomic markers.
Methods: Samples collected from 91 patients randomised to STRESS-L were profiled for immune and metabolomic markers. A panel of pro- and anti-inflammatory cytokines were measured through commercially acquired multiplex Luminex assays and statistically analysed by individual and cluster-level analysis (patient).
Bioinspired Assembly of Natural Polyphenol-Amino Acid Surfactants as Multifunctional Durable Coatings for Anticorrosion Fruit Packaging.
J Agric Food Chem
January 2025
College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, P. R. China.
Challenges emerge in the quest for highly efficient and biocompatible coatings to tackle microbial contamination. Here, we propose a bioinspired paradigm combining (-)-epigallocatechin gallate (EGCG) and l-arginine surfactants (LAM) as all-green building blocks for advanced coatings with superior performance. Molecular dynamics simulations reveal the natural assembly process of the EGCG/LAM supramolecular nanoparticles (ELA NPs).
View Article and Find Full Text PDFPolyproline-Polyornithine Diblock Copolymers with Inherent Mitochondria Tropism.
Adv Mater
January 2025
Príncipe Felipe Research Center, Polymer Therapeutics Lab., Valencia, 46012, Spain.
Mitochondria play critical roles in regulating cell fate, with dysfunction correlating with the development of multiple diseases, emphasizing the need for engineered nanomedicines that cross biological barriers. Said nanomedicines often target fluctuating mitochondrial properties and/or present inefficient/insufficient cytosolic delivery (resulting in poor overall activity), while many require complex synthetic procedures involving targeting residues (hindering clinical translation). The synthesis/characterization of polypeptide-based cell penetrating diblock copolymers of poly-L-ornithine (PLO) and polyproline (PLP) (PLO-PLP, n:m ratio 1:3) are described as mitochondria-targeting nanocarriers.
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