Regression Equations for Age Estimation of South Asian Population from Cells of Human Dental Pulp.

Mymensingh Med J

Dr Zeeshan Qamar, Assistant Professor, Department of OMFS & Diagnostic Sciences, Faculty of Dentistry, Riyadh Elm University, Riyadh, Saudi Arabia; Assistant Professor, Department of Oral Biology, Liaquat College of Medicine and Dentistry, Karachi, Pakistan; E-mail:

Published: April 2020

AI Article Synopsis

  • Improved healthcare has led to increased human life expectancy, sparking interest in studying the relationship between age and dental pulp cell counts, crucial for tooth vitality.
  • The study analyzed 220 tooth samples from Pakistani and Saudi Arabian individuals across two age brackets (6-30 years and 31-85 years) to determine correlations between dental pulp cell types (odontoblasts, subodontoblasts, fibroblasts) and age.
  • The findings revealed that dental pulp cell counts peak during early adulthood and decline with age, with developed regression equations accurately estimating individual ages based on cell counts, showing statistical consistency with actual age.

Article Abstract

Due to improved healthcare services the human life expectancy has improved, therefore the interest of understanding the effect of age on number of dental pulp cells count has increased being key for maintaining vitality of the tooth. The aim of this study was to investigate correlations between numbers of dental pulp cells odontoblasts (OCs), subodontoblasts (SOCs) and fibroblasts (FCs) with age, within different age groups for Pakistani and Saudi Arabian populations. A total number of 220 tooth samples were included in the study, comprising of 55-teeth for individuals aged groups between 6-30 years and 31-85 years for Group I and Group II of both Pakistani and Saudi Arabian populations respectively. The qualitative research was conducted at Riyadh Elm University, Riyadh, Saudi Arabia from February 2019 to July 2019. Regression equations (RE) for the estimation of individuals' age from dental pulp cell count were developed. The values of the correlations obtained for each RE indicate good fits for the equations obtained. The pulp cells were observed to upsurge till third decade of life, later were observed to decline with increasing age. Pearson correlation revealed positive relation between number of dental pulp cells with age for Group I whereas a significant negative relationship for individuals above 30 years above. RE generated using number of OCs, SOCs and FCs for determination of age with standard error estimate was ±3 and ±6 years for Pakistani population Group I (6-30 years) and Group II (31-85 years) respectively whereas, for Saudi Arabian population Group I and Group II it was ±4 years and ±9 years. The age estimates made by the number of dental pulp cells were not statistically significantly different (p>0.05) from chronological age.

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