Surgery increases the risk (by 20-fold) of venous thromboembolism (VTE), but there are prophylaxis methods (mechanical, pharmaceutical or combined) that safely reduce the incidence rate of VTE. The administration of prophylaxis requires a prior assessment of the risks associated with the patient and with the type of surgery. The Caprini and Rogers scales classify patients into four VTE risk categories (very low, low, moderate and high). In pharmacological prophylaxis, the risk of bleeding should also be assessed. At this time, the recommendation is to administer prophylaxis to all patients: mechanical prophylaxis for low, moderate or high risk with contraindications for the administration of heparin; combined with heparin for very high risk; and with drugs such as low-molecular-weight heparin, unfractionated heparin and fondaparinux for moderate to high risk. These measurements should be kept until full ambulation, discharge, or at least seven days (for major oncologic and bariatric surgery, maintain for four weeks).
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http://dx.doi.org/10.1016/j.rce.2020.04.017 | DOI Listing |
PLoS One
January 2025
Department of Neurology, Sichuan Taikang Hospital, Chengdu, Sichuan, China.
PLoS One
January 2025
Department of Clinical Nursing, School of Nursing and Public Health, University of Dodoma, Dodoma, Tanzania.
Background: Adolescents living with HIV face unique challenges, including mental health issues such as depression and cognitive dysfunction. Despite this significant burden, there is a lack of evidence focusing on this population. This study therefore aims to examine the moderating effects of biopsychosocial factors on the bi-directional relationship between HIV-related depression and cognitive function among adolescents living with HIV in the Mbeya region, Tanzania.
View Article and Find Full Text PDFIssues Ment Health Nurs
January 2025
School of Psychology, University of Nottingham, Nottingham, UK.
This study investigated the interrelationship between burnout, workload, and imposter syndrome among mental health nurses within the UK. Understanding their connections is crucial given the detrimental effects of these factors on workplace well-being. Despite extensive research on imposter syndrome in various healthcare professions, its exploration within nursing has been limited.
View Article and Find Full Text PDFAppl Neuropsychol Adult
January 2025
Jersey Shore University Medical Center, Neuropsychology Rehabilitation Services, Lifespan, Trinton Falls, NJ, USA.
In the field of neuropsychology, the accuracy of neuropsychological data interpretation has significant implications for both research and clinical practice. The process of test interpretation is fraught with challenges, and a lack of consensus among neuropsychologists can lead to discrepancies in assessment outcomes. Smith et al.
View Article and Find Full Text PDFJ Med Chem
January 2025
Graduate School of Innovative Life Science, University of Toyama, 3190 Gofuku, Toyama 930-8555, Japan.
Transthyretin (TTR), a plasma protein, undergoes transformation into amyloid fibers, leading to ATTRv amyloidosis, a disease characterized by organ deposition of TTR amyloid fibrils and subsequent organ failure. Developing compounds that bind and kinetically stabilize TTR is a crucial strategy in the treatment of ATTRv amyloidosis. In this study, we narrowed 651 pesticide-related compounds down to 14 possible TTR binders through in silico screening; subsequent in vitro analysis revealed that 7 of them exhibited amyloid fibril formation inhibition activity.
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