Background: This study will appraise the effect and safety of advanced nursing care (ANC) on psychological condition (PC) in patients with chronic heart failure (CHF).

Methods: The following databases will be sought from the beginning up to the February 29, 2020: MEDLINE, EMBASE, Cochrane Library, Web of Science, Scopus, the Cumulative Index to Nursing and Allied Health Literature, the Allied and Complementary Medicine Database, the Chinese Scientific Journal Database, and China National Knowledge Infrastructure. There are not language and publication status limitations related to any electronic databases. In addition, we will also identify conference proceedings, reference lists of included studies, and websites of clinical trials registry. Two reviewers will separately carry out study selection, data extraction, and study quality evaluation. Any inconsistencies will be solved by a third reviewer through discussion. RevMan 5.3 software will be utilized to carry out statistical analysis.

Results: This study will comprehensively summarize all potential evidence to systematically address the effects and safety of ANC on PC in patients with CHF.

Conclusion: The findings of the present study will help to determine whether ANC is effective or not on PC in patients with CHF.

Study Registration Number: INPLASY202040077.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306357PMC
http://dx.doi.org/10.1097/MD.0000000000020355DOI Listing

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