AI Article Synopsis
- Determining the location history of objects is important for health, commerce, and food safety, and using microbes can provide a cost-effective way to track provenance.
- Researchers developed a scalable microbial spore system capable of identifying object origins in under an hour, achieving high sensitivity and environmental safety.
- This system addresses challenges like persistence, scalability, and rapid detection, and is compatible with SHERLOCK technology for diverse applications.
Article Abstract
Determining where an object has been is a fundamental challenge for human health, commerce, and food safety. Location-specific microbes in principle offer a cheap and sensitive way to determine object provenance. We created a synthetic, scalable microbial spore system that identifies object provenance in under 1 hour at meter-scale resolution and near single-spore sensitivity and can be safely introduced into and recovered from the environment. This system solves the key challenges in object provenance: persistence in the environment, scalability, rapid and facile decoding, and biocontainment. Our system is compatible with SHERLOCK, a Cas13a RNA-guided nucleic acid detection assay, facilitating its implementation in a wide range of applications.
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| http://dx.doi.org/10.1126/science.aba5584 | DOI Listing |
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