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The concept of effective coverage radius use of the unlicensed high-frequency range in the operation of the 5G network.
Heliyon
November 2024
Department of Informatics, University of Žilina, Zilina, Žilina, Slovakia.
Economic expediency encourages mobile operators to deploy 5G networks in places with a high concentration of speed-demanding subscribers. In such conditions, sharp fluctuations in the volume of traffic with regulated requirements for the quality of service are inevitable. Note that 5G operates in the millimeter range.
View Article and Find Full Text PDFPrevalence and Impact of Recurrent Rejection on Pediatric Heart Transplant Recipients: A PHTS Multi-Institutional Analysis.
J Am Coll Cardiol
November 2024
Division of Pediatric Cardiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Background: Studies evaluating the prevalence and impact of recurrent rejection (RR) in pediatric heart transplant (HT) are sparse.
Objectives: The purpose of this study was to describe prevalence and impact of RR on cardiac allograft vasculopathy (CAV) and graft loss after pediatric HT.
Methods: Data on HT from January 1, 2000, to June 30, 2020, in the Pediatric Heart Transplant Society database were included.
A Patient-Centered Perspective on Changes in Personal Characteristics After Deep Brain Stimulation.
JAMA Netw Open
September 2024
Center for Neurological Restoration, Cleveland Clinic, Cleveland, Ohio.
Importance: Deep brain stimulation (DBS) results in improvements in motor function and quality of life in patients with Parkinson disease (PD), which might impact a patient's perception of valued personal characteristics. Prior studies investigating whether DBS causes unwanted changes to oneself or one's personality have methodological limitations that should be addressed.
Objective: To determine whether DBS is associated with changes in characteristics that patients with PD identify as personally meaningful.
Development and optimization of a diluted whole blood ELISpot assay to test immune function.
J Immunol Methods
October 2024
Department of Urology, University of Minnesota, Minneapolis, MN, United States of America; Center for Immunology, University of Minnesota, Minneapolis, MN, United States of America; Minneapolis VA Health Care System, Minneapolis, MN, United States of America. Electronic address:
Sepsis remains a leading cause of death worldwide with no proven immunomodulatory therapies. Stratifying Patient Immune Endotypes in Sepsis ('SPIES') is a prospective, multicenter observational study testing the utility of ELISpot as a functional bioassay specifically measuring cytokine-producing cells after stimulation to identify the immunosuppressed endotype, predict clinical outcomes in septic patients, and test potential immune stimulants for clinical development. Most ELISpot protocols call for the isolation of PBMC prior to their inclusion in the assay.
View Article and Find Full Text PDFFamilial Loss of a Loved One and Biological Aging: NIMHD Social Epigenomics Program.
JAMA Netw Open
July 2024
Carolina Population Center, University of North Carolina at Chapel Hill.
Importance: The link between familial loss of a loved one and long-term health decline is complex and not fully understood.
Objective: To test associations of losing a parent, sibling, child, or partner or spouse with accelerated biological aging.
Design, Setting, And Participants: Data from the National Longitudinal Study of Adolescent to Adult Health, a US population-based longitudinal cohort study, were analyzed.
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