Nagano and Yamanashi prefectures of Japan comprise an inland mountain area that extends widely north and south, with elevation varying greatly by location. Mosquitoes transmitting infectious disease have a diversity of habitats in Nagano and Yamanashi, and many species can be expected there. However, there have been few reports on mosquito fauna; in particular, little information is available on mosquitoes such as . The mosquito fauna was investigated to clarify their elevational distribution ranging from 317 to 1,534 m, focusing especially on , in 24 areas in Nagano and Yamanashi prefectures from July to September in 2012-16. Adult mosquitoes were collected using the Centers for Disease Control and Prevention traps in each area, in addition to larval mosquito collections at several temple and shrine precincts in each area. At sites where elevations were >800 m (14 sites), no adult were captured. In addition, larval were not collected at elevations >728 m (15 sites). was captured at 20 other sites (annual mean air temperature ranged from 9.4 to 15.2°C, July-September mean air temperature ranged from 19.9 to 25.0°C).
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http://dx.doi.org/10.2987/19-6902.1 | DOI Listing |
Front Oncol
January 2025
Department of Radiology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Nature
January 2025
Division of Cell Therapy, Chiba Cancer Center Research Institute, Chiba, Japan.
Cancer cells in the tumour microenvironment use various mechanisms to evade the immune system, particularly T cell attack. For example, metabolic reprogramming in the tumour microenvironment and mitochondrial dysfunction in tumour-infiltrating lymphocytes (TILs) impair antitumour immune responses. However, detailed mechanisms of such processes remain unclear.
View Article and Find Full Text PDFNeurochem Int
January 2025
Department of Neurology, Osaka University Graduate School of Medicine, Osaka, Japan; Department of Neurotherapeutics, Osaka University Graduate School of Medicine, Osaka, Japan; Mount Fuji Research Institute, Yamanashi Prefectural Government, Yamanashi, Japan. Electronic address:
Amyotrophic lateral sclerosis (ALS) is characterized by the mislocalization and abnormal deposition of TAR DNA-binding protein 43 (TDP-43). This protein plays important roles in RNA metabolism and transport in motor neurons and glial cells. In addition, abnormal iron accumulation and oxidative stress are observed in the brain and spinal cord of patients with ALS exhibiting TDP-43 pathology and in animal models of ALS.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Pediatrics, International University of Health and Welfare, Tokyo, Japan.
Dilated cardiomyopathy (DCM) is a progressive myocardial disorder characterized by impaired cardiac contraction and ventricular dilation. However, some patients with DCM improve when experiencing left ventricular reverse remodeling (LVRR). Currently, the detailed association between genotypes and clinical outcomes, including LVRR, particularly among children, remains uncertain.
View Article and Find Full Text PDFDisaster Med Public Health Prep
December 2024
Orange Home Care Clinic, Fukui, Fukui, Japan.
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