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| http://dx.doi.org/10.1513/AnnalsATS.201911-847IP | DOI Listing |
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Evaluating the impact of modeling choices on the performance of integrated genetic and clinical models.
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Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN; Center for Digital Genomic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN; Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN. Electronic address:
Purpose: The value of genetic information for improving the performance of clinical risk prediction models has yielded variable conclusions. Many methodological decisions have the potential to contribute to differential results. We performed multiple modeling experiments integrating clinical and demographic data from electronic health records (EHR) with genetic data to understand which decisions may affect performance.
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View Article and Find Full Text PDFStandardised Pressure Injury Prevention Protocol (SPIPP- Adult) Checklist 2.0: Language and Content Validity Study.
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Nursing Department, Faculty of Health Sciences, Karadeniz Technical University, Trabzon, Türkiye.
Introduction: Implementation of clinical practice guidelines, an important strategy in the prevention of pressure injuries, enables the nurse to interpret evidence-based guideline recommendations, reduce errors, ensure compliance and standardisation of complex processes, manage patient-related risks and systematically regulate all preventable conditions.
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Reassurance for Patients-Essential Not Optional.
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Appropriate patient reassurance is an essential feature of clinical practice. My recent experience as a patient, interpreted via my expertise as a health services researcher, led me to insights on ideal and suboptimal reassurance styles in the context of worrisome symptoms. Reassurance is complex: often poorly defined in the scientific literature, rarely rigorously studied, imperfectly understood, and requiring some adaptation to each patient situation.
View Article and Find Full Text PDFMulticenter retrospective study on advancements in diagnosis and laparoscopic treatment of hepatic echinococcosis in Xinjiang China.
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With the advancement of precise hepatobiliary surgery concepts, the diagnostic and therapeutic approaches for hepatic echinococcosis have undergone significant transformations. However, whether these changes have correspondingly improved patient outcomes remains unclear. A retrospective analysis of these changes will provide crucial guidance for the prevention and treatment of hepatic echinococcosis.
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