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Assessment of Four Essential Features of the Alive & Thrive Initiative to Improve Maternal, Infant, Young Child, and Adolescent Nutrition.
Matern Child Nutr
January 2025
ELEVATE Nutrition, Washington, District of Columbia, USA.
Alive & Thrive has been a major global nutrition initiative that aimed to learn how to improve maternal, infant, young child, and adolescent nutrition and health on a large scale. During 2009-2014, Alive & Thrive developed and implemented interventions to improve infant and young child feeding at scale in three countries. Subsequently, Alive & Thrive expanded its work to more than 15 geographies, including six country-specific and two regional programs, to additionally address maternal and adolescent nutrition while adding agriculture and social protection programs to improve maternal, infant, and young child nutrition.
View Article and Find Full Text PDFBig picture thinking of global PM-related COPD: Spatiotemporal trend, driving force, minimal burden and economic loss.
J Hazard Mater
January 2025
School of Urban Planning and Design, Peking University Shenzhen Graduate School, Shenzhen 518055, China. Electronic address:
Chronic obstructive pulmonary disease (COPD) is a leading global cause of morbidity and mortality, with increasing evidence linking long-term exposure to ambient fine particulate matter (PM) to accelerated lung function decline and exacerbation of COPD symptoms. This study aimed to assess the global burden of PM-related COPD from 1990 to 2021 and project future health and economic impacts. Using Mendelian randomization, the causal relationship between PM exposure and COPD was confirmed.
View Article and Find Full Text PDFSolution NMR goes big: Atomic resolution studies of protein components of molecular machines and phase-separated condensates.
Curr Opin Struct Biol
January 2025
Department of Chemistry, University of Toronto, Toronto, ON, M5S 3H6, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada; Department of Biochemistry, University of Toronto, Toronto, ON, M5S 1A8, Canada; Program in Molecular Medicine, Hospital for Sick Children Research Institute, Toronto, ON, M5G 0A4, Canada. Electronic address:
The tools of structural biology have undergone remarkable advances in the past decade. These include new computational and experimental approaches that have enabled studies at a level of detail - and ease - that were not previously possible. Yet, significant deficiencies in our understanding of biomolecular function remain and new challenges must be overcome to go beyond static pictures towards a description of function in terms of structural dynamics.
View Article and Find Full Text PDFCochrane corner: artificial intelligence for diagnosing exudative age-related macular degeneration.
Eye (Lond)
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Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom.
A multi-feature dataset of coated end milling cutter tool wear whole life cycle.
Sci Data
January 2025
School of Cyber Science and Engineering, Qufu Normal University, Qufu, 273165, China.
Deep learning methods have shown significant potential in tool wear lifecycle analysis. However, there are fewer open source datasets due to the high cost of data collection and equipment time investment. Existing datasets often fail to capture cutting force changes directly.
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