The design of optical resonant systems for controlling light at the nanoscale is an exciting field of research in nanophotonics. While describing the dynamics of few resonances is a relatively well understood problem, controlling the behavior of systems with many overlapping states is considerably more difficult. In this work, we use the theory of generalized operators to formulate an exact form of spatio-temporal coupled mode theory, which retains the simplicity of traditional coupled mode theory developed for optical waveguides. We developed a fast computational method that extracts all the characteristics of optical resonators, including the full density of states, the modes quality factors, and the mode resonances and linewidths, by employing a single first principle simulation. This approach can facilitate the analytical and numerical study of complex dynamics arising from the interactions of many overlapping resonances, defined in ensembles of resonators of any geometrical shape and in materials with arbitrary responses.
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http://dx.doi.org/10.1038/s41598-020-65293-6 | DOI Listing |
Sci Rep
December 2024
Shandong University of Science and Technology, College of Transportation, Qingdao, 266590, China.
The optimization of auto parts supply chain logistics plays a decisive role in the development of the automotive industry. To reduce logistics costs and improve transportation efficiency, this paper addresses the joint optimization problem of multi-vehicle pickup and delivery transportation paths under time window constraints, coupled with the three-dimensional loading of goods. The model considers mixed time windows, three-dimensional loading constraints, cyclic pickup and delivery paths, varying vehicle loads and volumes, flow balance, and time window constraints.
View Article and Find Full Text PDFNat Commun
December 2024
Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research, Ministry of Education of China, Key Laboratory of the Assembly and Application of Organic Functional Molecules of Hunan Province, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, Hunan, 410081, China.
Owning to the versatile nature in participation of Diels-Alder (D-A) reactions, the development of efficient approaches to generate active ortho-quinodimethanes (o-QDMs) has gained much attention. However, a catalytic method involving coupling of two readily accessible components to construct o-QDMs is lacking. Herein, we describe a palladium carbene migratory insertion enabled dearomative C(sp)-H activation to form active o-QDM species through the cross-coupling of N-tosylhydrazones with aryl halides.
View Article and Find Full Text PDFTalanta
December 2024
College of Food Science and Engineering, Northwest A&F University, Yangling, 712100, Shaanxi, China; Laboratory of Quality & Safety Risk Assessment for Agro-Products (Yangling), Ministry of Agriculture and Rural Affairs of the People's Republic of China, Yangling, 712100, China. Electronic address:
In the study, an eccentric heterogeneous core-shell nanomaterial Au@CuSe was simply and rapidly synthesized. This novel nano-structure exhibits superior colorimetric intensity, enhanced antibody coupling efficiency, and strong broadband absorption across the visible to near-infrared spectrum, with a photothermal conversion efficiency of 59.40%.
View Article and Find Full Text PDFBiosens Bioelectron
December 2024
Teaching and Research Office of Food Safety, School of Public Course, Bengbu Medical College, Bengbu, 233000, China. Electronic address:
The construction of structure-guided aptamers and the ultra-sensitive aptamer-based lateral flow assays (Apt-LFA) integrated detection method hold significant potential for food analysis. Using an engineered modified sequence strategy, we successfully developed the aptamer Cap-1-2M4, significantly enhancing its affinity for capsaicin (CAP) to 0.6197 ± 0.
View Article and Find Full Text PDFEur J Med Chem
December 2024
Swiss Tropical and Public Health Institute, Kreuzstrasse 2, 4123, Allschwil, Switzerland; University of Basel, P.O. Box CH-4003, Basel, Switzerland. Electronic address:
For over three decades, praziquantel (PZQ) has been the mainstay chemotherapy for prevention and treatment of schistosomiasis. The excessive use of PZQ, coupled with the lack of advanced drug candidates in the current anti-schistosomiasis drug development pipeline, emphasizes the genuine need for new drugs. In the current work, we investigated the antischistosomal potential of a new series of compounds derived from the privileged benzimidazole scaffold, which exhibited low micromolar IC potency in the range of 1.
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