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Large language models in rare disease: accuracy in addressing fibromuscular dysplasia questions.
Vasa
January 2025
Department of Cardiovascular Medicine, Section of Vascular Medicine, Heart Vascular and Thoracic Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Diagnostic and Therapeutic Approach to the Major Secondary Causes of Arterial Hypertension in Young Adults: A Narrative Review.
Cardiol Rev
October 2024
Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA.
Arterial hypertension in young adults, which includes patients between 19 and 40 years of age, has been increasing in recent years and is associated with a significantly higher risk of target organ damage and short-term mortality. It has been reported that up to 10% of these cases are due to a potentially reversible secondary cause, mainly of endocrine (primary aldosteronism, Cushing's syndrome, and pheochromocytoma/paraganglioma), renal (renovascular hypertension due to fibromuscular dysplasia and renal parenchymal disease), or cardiac (coarctation of the aorta) origin. It is recommended to rule out a secondary cause of high blood pressure (BP) in those patients with early onset of grade 2 or 3 hypertension, acute worsening of previously controlled hypertension, resistant hypertension, hypertensive emergency, severe target organ damage disproportionate to the grade of hypertension, or in the face of clinical or biochemical characteristics suggestive of a secondary cause of hypertension.
View Article and Find Full Text PDFRapidly Expanding Fusiform Abdominal Aortic Aneurysm without Stenotic Lesion Caused by Fibromuscular Dysplasia: A Rare Case.
Ann Vasc Dis
December 2024
Department of Cardiovascular Surgery, Aomori Prefectural Central Hospital, Aomori, Aomori, Japan.
Fibromuscular dysplasia (FMD) is an arterial disease characterized by fibrous arterial wall thickening and irregular proliferation and degeneration of smooth muscle cells in muscular arteries. Abdominal aortic aneurysms (AAA) are rare, with only a few reported cases. A characteristic feature of AAA is an aneurysm protruding forward near the terminal aorta with stenosis.
View Article and Find Full Text PDFCarotid Web Management in Symptomatic Patients: A Case Report and Literature Review.
Cureus
November 2024
Vascular Surgery, University Hospitals Leicester, Leicester, GBR.
The carotid web is a rare fibromuscular dysplasia disease of the internal carotid artery wall. It is a cause of thromboembolic stroke in a demographic of patients generally younger than those with atherosclerotic carotid artery disease. It is easy to miss the diagnosis without a high index of suspicion.
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