Objective: To study a role of executive functions in the development of organic emotionally labile (asthenic) disorder (OELD) and oppositional defiant disorder (ODD).
Material And Methods: The study included 66 patients, aged 6 to 8 years, including 36 children with OELD and 30 children with ODD. Fatigue was assessed by parents on a 10-point digital rating scale. SNAP-IV questionnaire for evaluation of severity of behavioral disorders, the "Strengths and Difficulties Questionnaire" for assessment of emotional and behavioral disorders, the anxiety test of P. Temple, M. Dorkey and V. Amen, A.R. Luria test for auditory-speech memory and the Test of Variables of Attention (TOVA) were used.
Results And Conclusion: A significantly greater severity of cognitive and emotional impairment in the group of children with OELD is identified. The data suggest that if the insufficiency of functions regulating the activation of behavior and impaired cognitive control of behavior is important in the pathogenesis of OELD, then behavioral self-regulation disorders associated with emotional reinforcement play a leading role in children with ODD.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.17116/jnevro202012004123 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Sex and APOE genotype modulate neuropsychological profile and depression in temporal lobe epilepsy.
Front Neurosci
January 2025
Institute for Biomedical Research and Innovation (IRIB), Italian National Research Council (CNR), Cosenza, Italy.
Introduction: Temporal lobe epilepsy is the most common form of focal epilepsy, often associated with cognitive impairments, particularly in memory functions, and depression. Sex and APOE ε4 genotype play a crucial role in modulating cognitive outcomes and depression in various neurological conditions like Alzheimer's disease. However, the combined effects of APOE genotype and sex on cognitive performance and depression in temporal lobe epilepsy have not been previously investigated.
View Article and Find Full Text PDFThe pulsatile brain, pulse pressure, cognition, and antihypertensive treatments in older adults: a functional NIRS study.
J Hum Hypertens
January 2025
Research Centre, Montreal Heart Institute, Montreal, QC, Canada.
Age-related arterial stiffness increases pulsatility that reaches the cerebral microcirculation, compromises cerebrovascular health and lead to cognitive decline. The presence of cardiovascular risk factors (CVRFs) such as high blood pressure can exacerbate this effect. Despite extensive research on the impact of antihypertensive treatments on reducing arterial stiffness, little is known about the impact of antihypertensive treatments on pulsatility in cerebral microcirculation.
View Article and Find Full Text PDFChronic kidney disease.
Nat Rev Dis Primers
January 2025
Division of Nephrology, Department of Medicine IV, Hospital of the Ludwig-Maximilians University, Munich, Germany.
Chronic kidney disease (CKD) is defined by persistent abnormalities of kidney function or structure that have consequences for the health. A progressive decline of excretory kidney function has effects on body homeostasis. CKD is tightly associated with accelerated cardiovascular disease and severe infections, and with premature death.
View Article and Find Full Text PDFDopaminergic Mechanisms of Cognitive Flexibility: An [F]Fallypride PET Study.
J Nucl Med
January 2025
Department of Nuclear Medicine, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Cognitive flexibility is the ability to appropriately adapt one's thinking and behavior to changing environmental demands and is conceptualized as an aspect of executive function. The dopamine system has been implicated in cognitive flexibility; however, a direct, that is, neurochemical, link to cognitive flexibility has not been shown yet. The aim of this study was, therefore, to investigate how cognitive flexibility is mediated by dopaminergic signaling in the ventromedial prefrontal cortex (vmPFC).
View Article and Find Full Text PDFAssociation Between Relative Hypothermia and Cognitive Function in Older Adults: A Cross-Sectional Study.
J Am Med Dir Assoc
January 2025
Department of Preventive Gerontology, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
Objectives: This study aimed to investigate the association between relative hypothermia measured by a wearable device and cognitive function, and to clarify whether relative hypothermia is a useful indicator for preventing poor cognitive function.
Design: Cross-sectional study.
Setting And Participants: The study included 103 community-dwelling older adults aged 60 to 90 years.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!