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A simple approach to fabricate chitosan-delivered avermectin controlled release microparticles for improved efficacy and reduced residues.
Int J Biol Macromol
January 2025
College of Chemistry and Pharmacy, Qingdao Agricultural University, Qingdao 266109, Shandong, PR China. Electronic address:
The presence of a synergistic effect between carrier and insecticide in controlled release formulations is highly desirable to improve efficacy to target pests and reduce insecticide use. Herein, controlled release microparticles of avermectin (AVM) were fabricated using natural chitosan (CTS) as a carrier by a pH adjustment method. The resulted AVM@CTS microparticles displayed high encapsulation efficiency (73.
View Article and Find Full Text PDFGreen Approach for Simultaneous Determination of Long Acting β-Agonists, their Organic Counterparts and Corticosteroids by HPLC Coupled with PDA Detector.
Ann Pharm Fr
January 2025
Department of Pharmaceutical Quality Assurance, SSR College of Pharmacy, Sayli Road, Silvassa, UT of Dadra and Nagar Haveli-396 230, India. Electronic address:
Objective: Accurate, precise and robust method was developed for the simultaneous estimation of long acting β2 agonist drugs (Formoterol fumarate, Salmeterol xinafoate and Vilanterol trifenatate) along with two organic counterparts (Xinafoic acid and Triphenyl acetic acid) and inhaled corticosteroids (Fluticasone propionate and Fluticasone furoate).
Material And Methods: The separation was carried out using C column (250 x 4.6 mm, 5 μ) with eluent comprising of 0.
International Society for Pediatric and Adolescent Diabetes Clinical Practice Consensus Guidelines 2024: Insulin and Adjunctive Treatments in Children and Adolescents with Diabetes.
Horm Res Paediatr
January 2025
Department of Pediatric Endocrinology, Rainbow Children's Hospital, Hyderabad, India.
The International Society for Pediatric and Adolescent Diabetes (ISPAD) guidelines represent a rich repository that serves as the only comprehensive set of clinical recommendations for children, adolescents, and young adults living with diabetes worldwide. This chapter builds on the 2022 ISPAD guidelines, and updates recommendations on the principles of intensive insulin regimens, including more intensive forms of multiple daily injections with new-generation faster-acting and ultra-long-acting insulins; a summary of adjunctive medications used alongside insulin treatment that includes details on pramlintide, metformin, glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RA) and sodium-glucose cotransporter inhibitors; and key considerations with regard to access to insulin and affordability to ensure that all persons with diabetes who need insulin can obtain it without financial hardship.
View Article and Find Full Text PDFAt least four groups of kratom consumers in the United States: latent-class analysis of motivations for kratom use.
Am J Drug Alcohol Abuse
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Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kratom is a plant with alkaloids acting at opioid, serotonergic, adrenergic, and other receptors. Consumers report numerous use motivations. To distinguish subgroups of kratom consumers by kratom-use motivations using latent-class analysis.
View Article and Find Full Text PDFWillingness to Use Long-Acting Injectable Pre-Exposure Prophylaxis among Adolescent Girls and Young Women in Kampala, Uganda.
AIDS Behav
January 2025
Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM) Uganda Research Unit, Kampala, Uganda.
Pre-exposure prophylaxis (PrEP) has proven to be a powerful tool in preventing HIV infection. There is limited information about the factors associated with willingness to use different PrEP modalities among adolescent girls and young women (AGYW) in Africa. We assessed willingness to use long-acting injectable PrEP (LAI-PrEP) among 14-24-year-old AGYW at high risk of HIV in Uganda, and associated factors determined using multivariable complementary log-log regression.
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