High-density lipoprotein and apolipoprotein A-I enhance activated protein C cytoprotective activity. High-density lipoprotein and apolipoprotein A-I significantly increase the rate at which activated protein C degrades cytotoxic extracellular histones.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284090PMC
http://dx.doi.org/10.1182/bloodadvances.2019001316DOI Listing

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