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Classification of Fibro-osseous Tumors in the Craniofacial Bones using DNA Methylation and Copy Number Alterations.
Mod Pathol
January 2025
Department of Pathology and Medical Biology, University Medical Center Groningen, Groningen, the Netherlands; Department of Pathology, Amsterdam University Medical Center, Amsterdam, the Netherlands. Electronic address:
Fibro-osseous tumors of the craniofacial bones are a heterogeneous group of lesions comprising cemento-osseous dysplasia (COD), cemento-ossifying fibroma (COF), juvenile trabecular ossifying fibroma (JTOF), psammomatoid ossifying fibroma (PsOF), fibrous dysplasia (FD), and low-grade osteosarcoma (LGOS) with overlapping clinicopathological features. However, their clinical behavior and treatment differ significantly, underlining the need for accurate diagnosis. Molecular diagnostic markers exist for subsets of these tumors, including GNAS mutations in FD, SATB2 fusions in PsOF, mutations involving the RAS-MAPK signaling pathway in COD, and MDM2 amplification in LGOS.
View Article and Find Full Text PDFEvaluation of stress patterns in teeth with endodontic treatment and periapical lesions as abutments for fixed prosthesis: a finite element analysis study.
BMC Oral Health
January 2025
Department of Agr. Machinery and Technology Engineering, Akdeniz University, Antalya, Turkey.
Background: Examining stress distributions in abutment teeth with periapical lesions is essential for understanding their biomechanical impact on dental structures and tissues. This study uses finite element analysis (FEA) to evaluate these stress patterns under occlusal forces, aiming to enhance treatment strategies and prosthetic designs.
Methods: Three FEA models were created: a healthy mandibular premolar (Model 1), a premolar with a single crown and a lesion repaired using a fiber-post (Model 2), and 3) a premolar with a lesion repaired using fiber-post to support a four-member bridge (Model 3).
Feasibility of the preauricular transparotid approach in open reduction and internal fixation of intracapsular mandibular condyle fracture.
J Craniomaxillofac Surg
January 2025
Department of Plastic Surgery, Korea University, College of Medicine, Korea University Anam Hospital, Seoul, Republic of Korea.
Mandibular condyle fractures pose surgical challenges owing to their proximity to the facial nerve and the complex temporomandibular joint anatomy. Traditional approaches limit exposure and hinder effective fracture management. The preauricular transparotid approach is a potential alternative.
View Article and Find Full Text PDFIs cranial anatomy indicative of fossoriality? A case study of the mammaliaform Hadrocodium wui.
Anat Rec (Hoboken)
January 2025
School of Geography, Earth & Environmental Sciences, University of Birmingham, Birmingham, UK.
Determining the ecology of fossil species presents considerable challenges due to the often fragmentary preservation of specimens. The mammaliaform Hadrocodium wui from the Jurassic of China is known only from the cranium and mandible but may have had a fossorial lifestyle. It shares morphological similarities with talpid moles and soricid shrews and is closely related to other fossorial mammaliaforms.
View Article and Find Full Text PDFA Retrospective Study on Correlation of Facial Fractures and Type of Trauma in Patients Admitted in Department of Maxillofacial Surgery of Stomatology National and Specialized Hospital, Kabul, Afghanistan.
Clin Cosmet Investig Dent
January 2025
Faculty of Medicine and Dentistry, Kabul University of Medical Sciences "Abu Ali Ibn Sina", Kabul, Afghanistan.
Background: Facial bone fractures represent a significant clinical challenge due to their prevalence and the complexity of treatment required. Understanding the demographic patterns, causes, and treatment outcomes of these injuries is crucial for improving patient care and developing targeted prevention strategies.
Objective: This study aims to analyze the demographic characteristics, etiological factors, anatomical distribution, and treatment modalities of patients presenting with facial bone fractures at Stomatology National and Specialized Hospital in Kabul, Afghanistan, during 2022.
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