AI Article Synopsis
- The study assessed how opioid use affects pregnant women with HIV and their babies, using data from 2002-2014.
- HIV-positive pregnant women were found to use opioids four times more often than those without HIV, leading to increased risks of complications such as early delivery and poor fetal health.
- The findings suggest that monitoring opioid usage and understanding the factors leading to its use in HIV-positive pregnant women could help reduce potential health risks for both mothers and infants.
Article Abstract
Objective: To assess patient- and hospital-level characteristics associated with opioid use in human immunodeficiency virus (HIV)-positive pregnant women and fetal health outcomes.
Methods: Using the 2002-2014 Nationwide Inpatient Sample database, we analyzed discharge records to describe the rates of opioid use among HIV-positive pregnant women. Logistic regression was used to quantify the magnitude of the association between exposure status and maternal-fetal outcomes.
Results: Opioid use was fourfold greater among HIV-positive pregnant women compared with their HIV-negative counterparts (odds ratio 4.0; 95% confidence interval 3.15-5.12). Relatively smaller but significant increases in the early onset of delivery, poor fetal growth, abortive pregnancy, and spontaneous abortion also were observed in association with HIV-positive status and opioid drug use during pregnancy.
Conclusions: An increased risk of negative maternal-fetal complications persists among HIV-positive women who use opioids during pregnancy. Focusing on predisposing factors and monitoring opioid dispensing may mitigate overuse or abuse in this vulnerable population.
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| http://dx.doi.org/10.14423/SMJ.0000000000001105 | DOI Listing |
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