Context: Facial melanoses decreases the quality of life (QoL). Melasma is the commonest cause but there are various other etiologies for facial pigmentation.
Aims: To study the clinical profile of patients with facial melanoses and the psychological burden in these patients.
Settings And Design: All patients having patchy or diffuse facial pigmentation attending the OPD in a tertiary care hospital for a period of 1 year were included in this hospital based cross-sectional study.
Subjects And Methods: The type, extent, and distribution of the pigmentation was noted and tabulated in all patients. All patients were explained about Skindex-16 questionnaire and asked to complete it.
Statistical Analysis Used: Student -test (two tailed, independent) was used to find the significance of study parameters on continuous scale between two groups. Chi-square/Fisher Exact test was used to find the significance of study parameters on categorical scale between two or more groups. Correlation was performed using Spearman corrélation.
Results: The total number of cases studied was 238 of which 186 (78.2%) were females and 52 (21.8%) were males. The most common diagnosis was melasma seen in 73% of cases. Other conditions noted were phototanning (5.8%), post-inflammatory hyperpigmentation (5.8%), Lichen planus pigmentosus (4.2%), freckles (3.7%), and Nevus of Ota (1.6%). Skindex-16 score against different grades of pigmentation showed that the mean Skindex-16 score was higher in severe cases but there was no statistically significant difference between the groups.
Conclusions: The extent and severity of facial pigmentation and the decrease in the QoL are not proportional.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247630 | PMC |
http://dx.doi.org/10.4103/idoj.IDOJ_209_19 | DOI Listing |
Int J Mol Sci
December 2024
Center for Bioscience Research and Education, Utsunomiya University, Tochigi 321-8505, Japan.
Little is known about the anti-pigmenting effects of skin-whitening agents on solar lentigos (SLs). To characterize the anti-pigmenting effects of a newly designed derivative ascorbyl glucoside-arginine complex (AGAC) on SLs, lotions with or without 28% AGAC were applied twice daily for 24 weeks in a double-blind half-face study of 27 Japanese females with SLs. The pigmentation scores and skin colors of previously selected SLs on the right and left sides of the faces of the subjects were evaluated using a photo-scale, a color difference meter and a Mexameter.
View Article and Find Full Text PDFDermatol Reports
November 2024
Dermatology Clinic, Maggiore Hospital, University of Trieste, Italy.
Riehl's melanosis (RM) is a pigmentary disorder, more common in individuals with dark skin phototypes, considered a form of pigmented contact dermatitis. In this paper we present a case of RM due to the rubber component of a work facial mask in which dermoscopy and patch test were the most important tools to help physicians in diagnosis. In addition, we reviewed the main dermoscopic clues that may be useful in differential diagnosis with other facial pigmentary disorders.
View Article and Find Full Text PDFJ Cosmet Dermatol
January 2025
Department of Dermatology, Peking University Shenzhen Hospital, Shenzhen, China.
Background: Melasma, a common skin pigmentation disease, can negatively impact patients' mental health, social interactions, and physical appearance. Although we now have several treatments accessible, such as medicines, chemical peels, and phototherapy, which can help ease symptoms to some extent, the requirement for a long-term effective and safe treatment for patients is far from met. In the face of this problem, microneedling, as an innovative treatment, provides a new avenue for treating melasma.
View Article and Find Full Text PDFAust J Gen Pract
December 2024
BPharm (UQ), Senior Pharmacist, Logan Hospital, Logan, Qld.
Background: Melasma, a condition characterised by hyperpigmented patches on the face, is one of the common skin conditions in women seeking treatment from primary care practitioners (PCPs). Several treatment modalities are available for PCPs as well as dermatologists. Each treatment option has its pros and cons, including accessibility and cost.
View Article and Find Full Text PDFArch Dermatol Res
November 2024
Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Zagazig University, Zagazig, Sharkia, Egypt.
Melasma is an acquired dysfunction of melanogenesis, that poses a major therapeutic challenge and tends to recur after therapy. Several combination therapies are being tested nowadays for the treatment of melasma, with promising results. Metformin, an anti-diabetic medication, seems to inhibit melanogenesis by different mechanisms.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!