Altogether 276 male patients with duodenal ulcer (DU), 45 with the preulcerative condition (PUC) and 70 with gastroduodenitis were examined. Anxiety-depressive disorders were most frequently revealed in all the groups. The frequency of hypochondriac fixation in DU increased. The neurohormonal "basis" of affective rigidity is formed during PUC. Specific variants of neurohormonal rearrangement in the transformation of PUC into DU were revealed in depressive, anxiety and hysterical manifestations.
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