Change in Warthin's tumor incidence: a 20-year joinpoint trend analysis.

Eur Arch Otorhinolaryngol

Department of Otorhinolaryngology, Gaziantep University, Gaziantep, Turkey.

Published: December 2020

Purpose: The incidence of Warthin's tumor (WT) has increased worldwide. In this study, we aimed to evaluate the incidence of WT in our hospital, which provides health care for an extremely large population.

Methods: We retrospectively evaluated 573 patients, comprising 345 males and 228 females, who all experienced parotid tumor for the past 20 years. Patients with WT that were operated in the last 20 years were evaluated according to the number of patients per year to determine the annual WT increase trend.

Results: In the distribution of WT over the years of surgery, the ratio of WT to all tumors irregularly changed. Furthermore, the total number of parotidectomies per year increased in time. We investigated whether WT had any increasing trend over the years. The annual percentage change (APC) of WT was calculated, and according to the segmented regression analysis, the APC was insignificant (APC = 4.3, 95% CI = - 3.6-12.9, P = 0.300).

Conclusion: The incidence of WT has increased across the world. However, in our study, no significant APC was observed according to the segmented regression analysis.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00405-020-06081-wDOI Listing

Publication Analysis

Top Keywords

warthin's tumor
8
segmented regression
8
regression analysis
8
change warthin's
4
incidence
4
tumor incidence
4
incidence 20-year
4
20-year joinpoint
4
joinpoint trend
4
trend analysis
4

Similar Publications

This study explores the role of irisin and interleukins in parotid tumors by determining the tissue staining intensity of irisin, the salivary and plasma levels of irisin, and the plasma levels of IL-4, IL-6, IL-10 and TNF-alpha in individuals with parotid tumors. Forty-eight patients and forty healthy individuals were included to the study and allocated into four group. Benign Group I (pleomorphic adenoma), Group II (Warthin's tumor), Group III (mucoepidermoid carcinoma) and Group IV (benign parotid control group, healthy control group).

View Article and Find Full Text PDF

A Rare Diagnosis of Parotid Gland Follicular Lymphoma Arising in Warthin Tumor: Case Report and Literature Review.

Medicina (Kaunas)

December 2024

Oral and Maxillofacial Surgery Department, Barzilai University Medical Center, Ben Gurion University of the Negev, Beer Sheva 8443944, Israel.

: A Warthin tumor is a benign salivary gland neoplasm, mostly found in the parotid gland. The number of reported Warthin tumors has increased over the years due to better diagnostic modalities and health system modernization. Warthin tumor rarely transforms into a malignant tumor; in this work, we present all cases reported in the English literature of different types of lymphomas within Warthin tumors.

View Article and Find Full Text PDF

The Impact of Inflammation on the Etiopathogenesis of Benign Salivary Gland Tumors: A Scoping Review.

Int J Mol Sci

November 2024

Department of Otolaryngology, Academy of Applied Medical and Social Sciences, 82-300 Elblag, Poland.

Salivary gland tumors are rare head and neck tumors constituting up to 6% of all head and neck neoplasms; despite being mostly benign, these tumors present in diverse histological subtypes, making them challenging to diagnose and treat. Our research aims to investigate the link between inflammation and tumorigenesis within the salivary glands based on the literature regarding the etiopathogenesis of benign salivary gland tumors. This scoping review was conducted following the PRISMA extension for scoping reviews and reporting guidelines.

View Article and Find Full Text PDF
Article Synopsis
  • Warthin's tumor is a common benign tumor in the parotid gland, often appearing in multiple places or in both glands at the same time in 20% - 30% of cases.
  • This case report highlights a rare instance of Warthin's tumor that occurred simultaneously in both parotid glands and outside the parotid area.
  • The low occurrence of such cases may be underestimated, and raising awareness could help doctors improve diagnosis and treatment for patients.
View Article and Find Full Text PDF

Purpose: BSND is a chloride channel subunit that is expressed in the normal salivary gland. We aimed to validate the utility of BSND immunohistochemistry in the differential diagnosis of oncocytic salivary gland neoplasms.

Methods: BSND immunohistochemistry was performed in a retrospective cohort of 93 salivary gland lesions, enriched with tumors with oncocytic features and histologic variants of mucoepidermoid carcinoma (MEC).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!