Multinucleate cell angiohistiocytoma: an uncommon cutaneous tumor.

An Bras Dermatol

Department of Dermatology, Faculdade de Medicina do ABC, Santo André, SP, Brazil.

Published: August 2020

AI Article Synopsis

  • - Multinucleate cell angiohistiocytoma is a rare, non-cancerous skin growth primarily seen in middle-aged women, typically presenting as painless, purple bumps on the hands and feet.
  • - The condition features specific microscopic traits, such as enlarged small blood vessels, thickened collagen in supportive tissue, and the presence of giant cells with multiple nuclei.
  • - A case study highlights a 62-year-old woman diagnosed with this condition who opted out of treatment due to its benign nature, emphasizing key clinical and immunohistological characteristics of the disorder.

Article Abstract

Multinucleate cell angiohistiocytoma is a rare, benign vascular proliferation of unknown etiology. It occurs mainly in middle-aged women and usually affects the acral regions; the lesions appear as discrete, grouped, and asymptomatic violaceous papules. Histopathology shows proliferation and dilated small vessels in the papillary dermis, fibrous stroma with thickened collagen bundles, and multinucleated giant cells. To date, there are approximately 140 cases described in the indexed literature. This report presents the case of a 62-year-old woman with a typical clinical condition, who chose not undergo treatment, considering the benign character of her illness. The clinical and immunohistological aspects of this unusual dermatological entity are emphasized.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335878PMC
http://dx.doi.org/10.1016/j.abd.2019.10.005DOI Listing

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