Rapid, simple and green solid phase extraction based on polyaniline nanofibers-mat for detecting non-steroidal anti-inflammatory drug residues in animal-origin food.

In this study, polyaniline modified polyacrylonitrile nanofibers mat (PANI NFsM) was prepared as a novel adsorbent for the solid-phase extraction (SPE) of non-steroidal anti-inflammatory drug residues in meat or egg samples. The solvent extracts of samples were simply diluted with water to perform the SPE, and then the eluent was directly analyzed. Significant reduction of the matrix effect was obtained after SPE using only 5 mg of PANI NFsM. The entire sample preparation time is 5-10 times lower than the existing methods. The limits of detection of the target analytes ranging from 0.6 to 12.2 µg kg had already met the demand of food safety monitoring by only 1 g sample. The recoveries ranged from 85.18% to 107.31%, with the intra-day and inter-day relative standard deviations of 2.74% to 16.01%, revealing satisfactory accuracy and precision. Finally, real samples analyses were applied to verify the practicability of the method.