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http://dx.doi.org/10.1093/ajhp/zxaa105 | DOI Listing |
Am J Health Syst Pharm
June 2020
College of Pharmacy California Northstate University, Elk Grove, CA.
PLoS One
April 2014
College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, Republic of Korea ; Dong-A ST Research Institute, Yongin-si, Gyeonggi-do, Republic of Korea.
Background: Agonists of glucagon-like peptide-1 receptor (GLP-1R) and glucokinase activators (GKA) act as antidiabetic agents by their ability protect beta cells, and stimulate insulin secretion. Oxidative and endoplasmic reticulum (ER) stresses aggravate type 2 diabetes by causing beta cell loss. It was shown that GLP-1R agonists protect beta cells from oxidative and ER stresses.
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