Comparative physiological analysis suggested evolutional direction of typical organization of the blood orthostatic regulation and its dependence upon the posture status in pronograde animals (rats, rabbits, cats, dogs) as well as in primates (humans, monkeys). Data on the evidence of functional adaptation of cardiovascular system under the conditions of experimental bipedal posture in monkeys are presented and the meaning of blood regulation according to the gravity factor in the development of arterial hypertension is discussed.
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