A case of xanthogranulomatous orchitis and its preoperative diagnostic challenges.

Urol Case Rep

Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar.

Published: September 2020

Xanthogranulomatous orchitis (XGO) is an extremely rare inflammatory disease of the testis which can mimic testicular tumors. We report a 42-year-old man who presented with left scrotal swelling for one-month duration associated with pus discharge from the overlying scrotal skin. Scrotal ultrasonography revealed an atrophic heterogenous left testis with scrotal wall collection. Surgical scrotal exploration with left simple orchidectomy was performed. By histopathology, the diagnosis of XGO was rendered. The preoperative diagnosis of XGO can very challenging and the diagnosis mainly relies on histopathologic examination. Adequate pathologic sampling is essential to rule out the possibility of co-existing testicular neoplasms.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243048PMC
http://dx.doi.org/10.1016/j.eucr.2020.101248DOI Listing

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Article Synopsis
  • Xanthogranulomatous orchitis (XGO) is a rare, benign condition that affects testicular tissue, causing significant damage due to lipid-laden macrophages infiltrating the area.
  • An 80-year-old man with chronic pyocele experienced left-sided scrotal swelling and was diagnosed preoperatively with XGO via ultrasound, leading to a left orchidectomy.
  • Histopathological examination confirmed the diagnosis by revealing damage to seminiferous tubules and highlighted the importance of proper diagnosis to differentiate XGO from testicular tumors, reinforcing the necessity of histopathology in treatment decisions.
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Introduction: Xanthogranulomatous inflammation is a rare nonneoplastic and chronic inflammatory process, characterized by proliferation of foamy macrophages resulting in damage and necrosis of the affected tissue. Involvement of the testis/epididymis by the disease is a rare event.

Methods: A case series of four male patients diagnosed with xanthogranulomatous epididymitis/orchitis (XGEO) at our institute was reviewed.

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Unlabelled: Xanthogranulomatous orchitis is a rare non-malignant condition. This study reports a new case of xanthogranulomatous orchitis in a 77-year-old male, who presented with acute right scrotal mass. Ultrasound and computed tomography showed a heterogenous lesion involving the testis, with a loculated collection in the overlying scrotal wall.

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Xanthogranulomatous epididymo-orchitis: A case report with review of the literature.

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Kscien Organization, Hamdi Str, Azadi Mall, Sulaimani, Kurdistan, Iraq.

Introduction: Xanthogranulomatous orchitis is an extremely rare condition of the test is marked by the necrosis and effacement of testicular parenchyma by an inflammatory process. The current study aims to report a case of xanthogranulomatous epididymo-orchitis.

Case Report: A 35-year-old man presented with a history of recurrent attacks of dull pain and swelling of the right side of the scrotum for 3 weeks.

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