Coronavirus disease 2019 (COVID-19), the current uncontrolled outbreak of infectious disease, has caused significant challenges throughout the world. A reliable rapid diagnostic test for COVID-19 is demanded worldwide. The real-time reverse transcriptase polymerase chain was one of the most quickly established methods in the novel viral pandemic and was considered as the gold standard for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this report, we illustrate our experience of applying a protocol from the Taiwan CDC and achieving assay optimization in the immediate circumstances to meet the urgent medical and public health needs.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278012 | PMC |
| http://dx.doi.org/10.3390/diagnostics10050333 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Associations of Pregnancy Timing Relative to the COVID-19 Pandemic, Maternal SARS-CoV-2 Infection, and Adverse Perinatal Outcomes.
Ann Epidemiol
January 2025
South Carolina SmartState Center for Healthcare Quality, South Carolina, USA; Department of Health Promotion, Education and Behavior, University of South Carolina Arnold School of Public Health, Institution address: 915 Greene Street, Columbia, SC 29208, USA. Electronic address:
Purpose: To examine associations between COVID-19 pandemic and maternal SARS-CoV-2 infection with perinatal outcomes.
Methods: We conducted a retrospective cohort study of 189,097 singleton births in South Carolina (2018-2021). Pregnancy timing relative to the pandemic was classified as pre-pandemic (delivered before March 1, 2020), partial pandemic overlap (conceived before and delivered during the pandemic), or pandemic (conceived and delivered during the pandemic).
Trends and Disparities in Parkinson's Disease Mortality in the United States with Predictions Using Machine Learning.
NeuroSci
January 2025
Department of Medicine, Creighton University, Omaha, NE 68178, USA.
Background: Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by the degradation of dopaminergic pathways in the brain. As the population in the United States continues to age, it is essential to understand the trends in mortality related to PD. This analysis of PD's mortality characterizes temporal shifts, examines demographic and regional differences, and provides machine-learning predictions.
View Article and Find Full Text PDFOptimizing Masks and Random Screening Test Usage within K-12 Schools.
MDM Policy Pract
January 2025
Department of Industrial and Systems Engineering, North Carolina State University, Raleigh, NC, USA.
Unlabelled: COVID-19 tremendously disrupted the global health system. People of all ages were at risk of becoming infected. Frequent school closures raised concerns about both the physical and mental health of school-age children.
View Article and Find Full Text PDFDevelopment of a Komagataella phaffii cell factory for sustainable production of ( +)-valencene.
Microb Cell Fact
January 2025
Xianghu Laboratory, Hangzhou, 310027, China.
Background: Sesquiterpene ( +)-valencene is a characteristic aroma component from sweet orange fruit, which has a variety of biological activities and is widely used in industrial manufacturing of food, beverage and cosmetics industries. However, at present, the content in plant sources is low, and its yield and quality would be influenced by weather and land, which limit the supply of ( +)-valencene. The rapid development of synthetic biology has accelerated the construction of microbial cell factories and provided an effective alternative method for the production of natural products.
View Article and Find Full Text PDFToward a Computable Phenotype for Determining Eligibility of Lung Cancer Screening Using Electronic Health Records.
JCO Clin Cancer Inform
January 2025
Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL.
Purpose: Lung cancer screening (LCS) has the potential to reduce mortality and detect lung cancer at its early stages, but the high false-positive rate associated with low-dose computed tomography (LDCT) for LCS acts as a barrier to its widespread adoption. This study aims to develop computable phenotype (CP) algorithms on the basis of electronic health records (EHRs) to identify individual's eligibility for LCS, thereby enhancing LCS utilization in real-world settings.
Materials And Methods: The study cohort included 5,778 individuals who underwent LDCT for LCS from 2012 to 2022, as recorded in the University of Florida Health Integrated Data Repository.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!