Topical application is an important administration route for drugs requiring local action on the skin, thereby avoiding their systemic absorption and adverse side effects. L. (syn. Spenn.), popularly known as rosemary, is an aromatic plant with needle-like leaves belonging to the family. Rosemary has therapeutic properties and has been used in the folk medicine, pharmaceutical, and cosmetics industries, mainly for its antioxidant and anti-inflammatory properties, which are attributed to the presence of carnosol/carnosic and ursolic acids. The therapeutic use of rosemary has been explored for the treatment of inflammatory diseases; however, other uses have been studied, such as wound healing and skin cancer and mycoses treatments, among others. Besides it therapeutic uses, rosemary has potential applications in cosmetic formulations and in the treatment of pathological and non-pathological conditions, such as cellulite, alopecia, ultraviolet damage, and aging. This review aims to critically discuss the topical applications of rosemary found in the literature while also offering relevant information for the development of topical formulations of its bioactive compounds.
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| http://dx.doi.org/10.3390/plants9050651 | DOI Listing |
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Instituto de Biología Molecular y Celular de Rosario (IBR)-Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Ocampo y Esmeralda S/N, S2002 FHN, Rosario, Argentina; Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario (UNR), Suipacha 590, S2002LRK, Rosario, Argentina. Electronic address:
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Article Synopsis
- A study explored the use of rosemary (Rosmarinus officinalis) as a natural herbicide due to its plant growth-inhibitory effects, specifically through the compound carnosic acid.
- Researchers analyzed how seasonal variations affect carnosic acid levels and phytotoxicity in rosemary leaves collected from two locations in Tunisia during 2011-2012.
- Results indicated that rosemary leaves had the highest carnosic acid concentration and growth inhibition effects during summer, suggesting that environmental factors like temperature and elevation play a significant role in these variations.
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