AI Article Synopsis
- Research focused on the antibacterial, antioxidant, and anti-type 2 diabetes activities of Mart. plant extract fractions, identifying a new biflavonoid compound named macrophylloflavone.
- Macrophylloflavone demonstrated significant antibacterial effects against specific bacterial strains and showed strong antioxidant activity in comparison to established controls.
- Treatment with macrophylloflavone led to a reduction in blood glucose levels in diabetic rats, indicating its potential as an effective agent for combating diabetes.
Article Abstract
Investigations of antibacterial, antioxidant, and anti-type 2 diabetes mellitus activities have been carried out on Mart. plant extract fractions. An isolate from a fraction of ethyl acetate extract was characterized with spectroscopic data. A new biflavonoid compound was found to have a skeleton of 5,7,4',5″,7″,3‴,4‴-heptahydroxyflavanone[3-6″] flavones which was named macrophylloflavone (). The compound was evaluated for its antibacterial activity against ATCC 25922 and ATCC 25923 with cephazolin as a positive control, antioxidant assay against 2,2 diphenyl-1-picrylhydrazyl (DPPH) with ascorbic acid as the positive control, and anti-type 2 diabetes mellitus treatment with metformin as a positive control. The biflavonoid compound exhibited a good inhibition for bacteria and free radical DPPH. Furthermore, biflavonoid compound treatment on the diabetic rats suggested its ability to decrease the blood glucose level. This study provided evidence that the plant has antibacterial, antioxidant, and antidiabetic properties.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240784 | PMC |
| http://dx.doi.org/10.1155/2020/2983129 | DOI Listing |
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