Antimicrobial and Anti-Inflammatory Activity of Some L. (Fabaceae) Species Growing in Turkey.

Objectives: The present study aimed to evaluate the antimicrobial and anti-inflammatory activities of methanol extracts and n-hexane, ethyl acetate, chloroform, and water fractions of five species, namely subsp. , and , growing in Turkey.

Materials And Methods: The antimicrobial activities were screened against ATCC 29213, ATCC 6633, ATCC 25922, ATCC 27853, and ATCC 10231. Broth dilution was used to determine the antimicrobial activities of extracts and fractions. anti-inflammatory activity of these extracts and fractions was determined using human red blood cell membrane stabilization.

Results: The results demonstrated that ethyl acetate fractions of the tested species exhibited higher antimicrobial activity than the other extracts. Among all of the tested extracts and fractions, the highest anti-inflammatory activity was detected in water fractions. Furthermore, water fractions of s showed better anti-inflammatory activity than acetylsalicylic acid and diclofenac sodium, which were used as standard drugs in this assay.

Conclusion: The results indicate the membrane stabilizing effect of the various extracts and fractions of the species and could constitute preliminary work for anti-inflammatory activity experiments.