Objectives: Ethanolic extracts of the mushroom species , and were investigated for their polyphenolic contents and biological activities.

Materials And Methods: The radical scavenging activity of the extracts was evaluated by 2,2-diphenyl-1-(2,4,6-trinitrophenyl) (DPPH) method and their polyphenolic compounds were determined by high performance liquid chromatography (HPLC) analysis. Furthermore, the activity effects of mushroom extracts on the enzyme glutathione-S-transferase (GST) were also examined. Additionally, the antimicrobial activity of mushroom extracts was evaluated by disc diffusion method.

Results: Ethanolic extract of demonstrated the highest total phenolic content and total flavonoid contents, with 227.23±4.96 mg gallic acid equivalent/g and 42.14±0.20 quercetin equivalent/g, respectively. The highest DPPH radical scavenging activity was observed for ethanolic extracts of , with 10.687±1.643 µg/mL IC. HPLC analysis demonstrated that was composed of ferulic acid, gallic acid, and myricetin compounds. The highest GST enzyme activity effect was detected with the ethanol extracts of and . None of the mushroom extracts demonstrated significant inhibition of the bacterial strains used.

Conclusion: These results indicate that may be proposed as a new potential source of natural medicine and its potential may be related to its polyphenolic content, which needs further investigation.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227972PMC
http://dx.doi.org/10.4274/tjps.galenos.2018.03274DOI Listing

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