Small Molecule Effectors of Myosin Function.

Adv Exp Med Biol

Hannover Medical School, Institute for Biophysical Chemistry, Hannover, Germany.

Published: August 2020

Several small molecule effectors of myosin function that target the motor domains of myosin classes I, II, V, and VI have been identified. Four distinct binding sites in the myosin motor domain have been reported with unique properties and mechanisms of action. This chapter describes the structural basis and activities of known small molecule effectors that allosterically target the myosin motor domain.

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http://dx.doi.org/10.1007/978-3-030-38062-5_5DOI Listing

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