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Recurrent painful blisters over the right foot.
JAAD Case Rep
January 2025
Department of Dermatology, National University Hospital, Singapore, Singapore.
Alterations on Nailfold Videocapillaroscopy in Myelodysplastic Syndrome and Onychomycosis in a Female Smoker: Microvascular Dysfunction Without Connective Tissue Disease.
Int J Rheum Dis
December 2024
Department of Rheumatology of Lucania-UOSD of Rheumatology, "Madonna delle Grazie" Hospital, Matera, Italy.
A 58-year-old female smoker diagnosed with myelodysplastic syndrome (MDS) presented with Raynaud's phenomenon and a "scleroderma-like" pattern on nailfold capillaroscopy. The capillaroscopic abnormalities were observed across all fingers, including those without clinical manifestations of onychomycosis. Over a two-year follow-up, there was no evidence of clinical or serological progression toward a connective tissue disease, particularly systemic sclerosis.
View Article and Find Full Text PDFLivedoid vasculopathy in hemoglobinopathy-associated chronic leg ulcers.
Ann Hematol
December 2024
Division of Hematology, Department of Medicine, UNC Chapel Hill School of Medicine, Chapel Hill, NC, United States of America.
Chronic leg ulceration is a debilitating manifestation of hemoglobinopathies, and best management is uncertain. Livedoid vasculopathy (LV) is a cutaneous non-inflammatory thrombotic vasculopathy treated with anticoagulation that has been identified in hemoglobinopathy-associated chronic leg ulceration. However, most patients with hemoglobinopathy-associated ulcers do not undergo workup for secondary causes, and the prevalence and relevance of LV is unclear.
View Article and Find Full Text PDFRadial cortex transverse distraction help to treat the Raynaud's phenomenon.
Sci Rep
December 2024
Department of Hand Surgery, Department of Orthopedics, Qilu Hospital of Shandong University, #107 Wenhua Xilu, Jinan, China.
Article Synopsis
- - Raynaud's phenomenon is a condition that causes spasms in blood vessels of the fingers, leading to reduced quality of life and often fails to respond to conventional treatments for over six months.
- - A study involving six patients who underwent a new procedure called radial cortex transverse distraction showed promising results, with significant improvements in pain, skin color, and healing of finger ulcers.
- - The follow-up indicated that this surgical method not only healed bone without complications but also effectively addressed symptoms of Raynaud's phenomenon, suggesting it could be a beneficial treatment option.
Addressing Diagnostic Challenges in Livedoid Vasculopathy: A Case Report on Interdisciplinary Management.
Cureus
October 2024
Internal Medicine, Veterans Affairs Caribbean Healthcare System, San Juan, PRI.
Livedoid vasculopathy (LV) is a rare vascular disorder characterized by excessive thrombosis of cutaneous vasculature, leading to dermal vessel occlusion, skin hypoxia, and ulceration. The nonspecific nature of its clinical manifestations often complicates diagnosis and inadequate oxygenation results in lesions that take longer to heal and are more susceptible to infections and complications. Despite its impact on patient quality of life, LV remains largely undocumented in the literature, making effective management challenging.
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