Background: Occipital nerve blocks are commonly used in the treatment of different types of refractory headaches. The procedure is considered safe, and serious complications have rarely been described.
Case Presentation: We report a serious complication of occipital nerve blockade secondary to the penetration of local anesthetic and non-steroidal anti-inflammatory drugs into the posterior fossa in a patient affected by type I Arnold Chiari malformation.
Conclusions: This case reminds that a proper injection technique is mandatory to avoid potentially severe complications when performing occipital nerve blocks.
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